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StockOptions Tris Buffer Kit


  • Focused, titrated buffer stocks for crystal screening, optimization, & production


  • pH 7.0 - 9.0 (21 reagents)
  • 0.1 pH increments
  • 1.0 M concentrated stocks
  • Tris pKa = 8.1


StockOptions Tris buffer kit is a preformulated, sterile filtered set of titrated buffer stocks. The StockOptions Tris buffer stock reagents are supplied as 1.0 M stock solutions in 10 ml volumes. Each StockOptions Tris buffer reagent is carefully titrated using hydrochloric acid. StockOptions Tris is comprised of 21 unique reagents covering the pH range of 7.0 to 9.0 in 0.1 pH unit increments.

Synonym: Trizma base or 2-Amino-2-(hydroxymethyl)-1,3-propanediol or THAM or Tris base or Tris(hydroxymethyl)aminomethane or Trometamol
Mr 121.14
CAS Number [77-86-1]
EC Number 201-064-4
Beilstein Registry Number 741883
Merck 14,9772
RTECS TY2900000
MDL Number MFCD00004679
PubChem Substance ID 24889854
Purity =99.8%
pKa = 8.1 at 25°C
Useful pH range of Tris = 7.0 - 9.0




StockOptions™ Tris


pH 7.0 to 9.0 in 0.1 pH unit increments



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1. Microscale Fluorescent Thermal Stability Assay for Membrane Proteins Structure, Volume 16, Issue 3, 11 March 2008, Pages 351-359 Alexander I. Alexandrov, Mauro Mileni, Ellen Y.T. Chien, Michael A. Hanson, Raymond C. Stevens

2. Crystallization and Preliminary X-ray Diffraction Analysis of the ArsC Protein from the Escherichia coli Arsenical Resistance Plasmid, R773. deMel, VSJ; Doyle, MA; Gladysheva, TB; Oden, KL; Martin, PD; Rosen, BP; Edwards, BFP. J Mol Biol 242, 701- 702, 1994.

3. Increasing the size of microcrystals by fine sampling of pH limits. A. McPherson. J. Appl. Cryst. (1995). 28, 362-365.