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Crystallography related career opportunities, post docs and related positions in the crystallography community. If you wish to place your job opportunity on the Hampton Research website, submit the details to tech@hrmail.com.


Research Associate Position, RA II or III

Description:

An opening is available in the drug discovery lab of Dr. Stephen Fesik for a research associate. The position requires a M.S. degree in biochemistry or a related field with 1-2 years of experience. The successful candidate will be trained initially but will work independently or with limited supervision on assigned duties thereafter. It’s a great opportunity to learn fragment screening by NMR and structure-based drug design. Please send CV or resume to kangsa.amporndanai@vanderbilt.edu

Duties include but not limited to:

•      Bacterial culture preparation in flasks and shakers

•      Protein purification, sample preparation and fragment screening by NMR

•      Protein-ligand complex co-crystallization and X-rays data collection


[Post Date: August 10, 2026]


Director – Sealy Center for Structural Biology (SCSB)

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Description:

University of Texas Medical Branch (UTMB) – Galveston, Texas
UTMB opened in 1891 as the nation’s first public medical school and hospital under unified leadership. What began as one hospital and medical school building in Galveston is now a major academic health sciences center of global influence, with medical, nursing, health professions and graduate biomedical schools; a world-renowned research enterprise; and a growing, comprehensive health system with hospitals on four campuses and a network of clinics.

The Director of the Sealy Center for Structural Biology (SCSB) will provide strategic and operational leadership for a multidisciplinary research center in the John Sealy School of Medicine, and dedicated to advancing brain health, diagnostic disease markers discovery, and therapeutics including vaccines and antibacterials research. The incumbent will lead a team of experienced researchers to work in collaboration with UTMB schools, academic departments, faculty and external collaborators.

The Director of the SCSB is eligible for faculty appointment and will oversee scientific programs, foster cross-campus and external collaborations, secure extramural funding, and guide the center’s growth as an internationally recognized center. This role requires a dynamic scientific leader with a strong record of extramural research, team building, and administrative excellence.

Educational Requirements & Experience

  • PhD, MD or equivalent degree in relevant scientific discipline.
  • A minimum of 10+ years of experience in structural biology, molecular biophysics, or related field.
  • Direct experience in impactful human health related research with sustained extramural funding.
  • Demonstrated experience in leadership roles within academia, research institutes, or major scientific organizations.
  • Strong publication record in high-impact peer-reviewed journals.
  • Experience managing multidisciplinary teams and complex research programs.
  • Eligibility for academic appointment at the rank of Associate Professor or Professor.
  • Experience leading large collaborative grants, consortia, or translational research initiatives is strongly preferred

Compensation: A competitive salary based upon educational background and experience. Additional benefits include a relocation allowance, a superior family benefits program and a state retirement program. 

Interested candidates please submit a Cover Letter and current/updated Curriculum Vitae (CV) to
Skott Harrington at saharrin@utmb.edu. A full job description will be provided

UTMB Health strives to provide equal opportunity employment without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, genetic information, disability, veteran status, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. As a Federal Contractor, UTMB Health takes affirmative action to hire and advance protected veterans and individuals with disabilities


[Post Date: August 7, 2026]


Research Associate / Postdoc (m/f/d)

View the Job Posting Here

Description:

The Institute of Biochemistry (Director: Univ.-Prof. Dr. Thomas Krey) at the University of Lübeck is seeking a full-time Research Associate / Postdoc (m/f/d) starting January 1, 2027 (currently 38.7 hours per week). The position is limited to a term of two years.

Our group uses mostly structural biology/biophysical techniques with a special focus on X-ray crystallography and cryo-electron microscopy to study viruses that constitute a threat for global health and their interactions with the immune system. The structural knowledge gained from our experiments can be used for structure-based design of antivirals and/or vaccines, i.e., has a direct translational potential.
The collaborative project of interest, funded by the VW Foundation, aims to develop antiviral drugs against the hepatitis E virus using structure-based methods, in particular X-ray crystallography. For this purpose the Universities of Frankfurt and Bochum, and the Fraunhofer Institute for Translational Medicine and Pharmacology form a vibrant network together with the University of Lübeck.

Tasks:

  • Production and crystallization of recombinant proteins
  • X-ray crystallographic analysis of protein crystals, data collection, and data analysis
  • Structure determination of proteins using X-ray crystallography
  • Identification of inhibitors using structural biology and in silico methods
  • Presentation of research results, both orally and in writing

Requirements:

  • Ph.D. in the natural sciences, preferably biochemistry, life sciences, chemistry or biology
  • Practical and theoretical knowledge in protein production, purification, and crystallization
  • Practical and theoretical knowledge in X-ray crystallographic structure determination of proteins
  • Fluency in spoken and written English
  • Ability and enthusiasm to work both independently and collaboratively in an interdisciplinary field and an international team
  • Interest in attending international conferences and presenting your own results
  • Creativity and enthusiasm in the search for innovative solutions

What we offer:

  • Collectively agreed remuneration including annual special payment (TV-L)
  • 30 days' holiday per year, plus 24.12. and 31.12. off work
  • Compatibility of family, private life and career through flexible working hours and part-time options (after individual assessment) as well as the possibility of mobile working
  • NAH.SH / Deutschland public transport ticket, participation in university sports, discounted canteen meals on campus and other corporate benefits
  • Health management programme “Healthy University”
  • A company pension scheme with high additional payments by the employer (VBL)
  • A secure job and a university environment with its typically lively and innovative character, with numerous events and further training opportunities

Classification will be in accordance with the automatic pay scale if the requirements of the pay scale are met up to the pay group listed above. A final job evaluation remains reserved.

The University of Lübeck is a modern and cosmopolitan employer. We welcome your application regardless of your age, gender, cultural and social background, religion, worldview, disability or sexual identity. We promote gender equality. In case of equal suitability, qualifications and professional performance, female applicants will be given preference. If you are an applicant with a severe disability, your application will be given preference in case of equal suitability.

Your contact for further questions:


+49 451 / 3101 3100


[Post Date: July 24, 2026]


Postdoctoral Research Associate - AI-driven Structure Analysis for Biological Discoveries

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Description:

Brookhaven National Laboratory’s National Synchrotron Light Source II (NSLS-II) seeks a Postdoctoral Research Associate for AI-driven Structure Analysis for Biological Discoveries for an on-site position in the Biological, Environmental and Planetary Science Division.

Advance the frontiers of structural biology by developing AI-driven methods for interpreting complex crystallographic data. This role will enable new discoveries in protein function, ligand binding, and dynamics through scalable computational analysis.

The ideal candidate would have a background and an interest in Computational Biology, Artificial Intelligence and Machine Learning.

Join a team of scientists at the leading macromolecular crystallography beamlines and at the computing center and contribute to science projects at the interface between AI method development and large-scale research facilities.

Essential Duties and Responsibilities

  • Develop workflows to improve models and maps to optimize likelihood for ligand placement

  • Develop AI/ML methods for automated interpretation of crystallography data for optimal ligand placement.

  • Build and curate training datasets linking electron density maps and structural models.

  • Design and evaluate AI models for 3D structural data.

  • Develop workflows for time-resolved crystallography data processing.

  • Integrate molecular dynamics with AI/ML methods.

  • Benchmark protein foundation model performance and integrate them with experimental analysis pipelines.

  • Work collaboratively with domain scientists, beamline scientists, and computational scientists.

  • Document methods and results.

Required Knowledge, Skills, and Abilities

  • Ph.D. in computer science, computational biology, physics, or related field.

  • Expertise in machine learning or AI.

  • Experience with molecular dynamics simulations and computational workflows.

  • Ability to work in teams.

  • Demonstrated track record of publications in the field.

Preferred Knowledge, Skills, and Abilities

  • Experience with structural biology, 3D ML and biology specific AI models.

  • Experience with HPC and surrogate modeling.

  • Familiarity with workflow orchestration tools.

Additional Information:

  • This position is a 2-year term, with the possibility of renewal contingent on performance and funding availability
  • Brookhaven Laboratory is committed to providing fair, equitable and competitive compensation. The full salary range for this position is $ $71,900-$119,000 / year. You will be placed at the level and salary commensurate with your experience. Salary offers will be commensurate with the final candidate’s qualification, education and experience and considered with the internal peer group
  • Candidates must have completed all degree requirements by the commencement of employment
  • BNL policy requires that after obtaining a PhD, eligible candidates for research associate appointments may not exceed a combined total of 5 years of relevant work experience as a post-doc and/or in an R&D position, excluding time associated with family planning, military service, illness or other life-changing events

Brookhaven National Laboratory is committed to employee success and we believe that a comprehensive employee benefits program is an important and meaningful part of the compensation employees receive. Review more information at BNL | Benefits Program

Brookhaven National Laboratory requires all non-badged personnel including visitors to produce a REAL-ID or REAL-ID compliant documentation to access Brookhaven National Laboratory – view more information at www.bnl.gov/real-id.  This is due to nationwide identification requirements for federal site access as required by the federal REAL ID Act.  Those not in possession of a REAL ID-compliant document will not be permitted to access the site which includes access to the Laboratory for interviews

As a U.S. Department of Energy laboratory, Brookhaven National Laboratory requires employees to obtain and maintain a DOE Uncleared Personal Identity Verification (UPIV) credential in accordance with Homeland Security Presidential Directive 12 (HSPD-12) requirements. The credentialing process is completed as part of onboarding and enables access to DOE facilities and information systems. As a condition of employment, the selected candidate must be able to obtain and maintain a UPIV credential. These requirements are established under DOE Order 206.2 Chg. 2, Identity, Credential, and Access Management (ICAM- Identity, Credential, and Access Management (ICAM)), and DOE Order 473.1A- Physical Protection Program- Physical Protection Program.

About Us

Brookhaven National Laboratory (www.bnl.gov) delivers discovery science and transformative technology to power and secure the nation’s future. Brookhaven Lab is a multidisciplinary laboratory with seven Nobel Prize-winning discoveries, 37 R&D 100 Awards, and more than 70 years of pioneering research. The Lab is primarily supported by the U.S. Department of Energy’s (DOE) Office of Science. Brookhaven Science Associates (BSA) operates and manages the Laboratory for DOE. BSA is a partnership between Battelle and The Research Foundation for the State University of New York on behalf of Stony Brook University. BSA salutes our veterans and active military members with careers that leverage the skills and unique experience they gained while serving our country, learn more at BNL | Opportunities for Veterans at Brookhaven National Laboratory.

Equal Opportunity/Affirmative Action Employer

Guided by our core values of integrity, responsibility, innovation, respect, and teamwork, Brookhaven Science Associates is an Equal Employment Opportunity Employer-Vets/Disabled. We are committed to fostering a respectful and collaborative environment that fuels scientific discovery. We consider all qualified applicants without regard to any characteristic protected by law. All qualified individuals are encouraged to apply. We ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.  *VEVRAA Federal Contractor

BSA employees are subject to restrictions related to participation in Foreign Government Talent Recruitment Programs, as defined and detailed in United States Department of Energy Order 486.1A. You will be asked to disclose any such participation at the time of hire for review by Brookhaven. The full text of the Order may be found at: https://www.directives.doe.gov/directives-documents/400-series/0486.1-BOrder-a/@@images/file


[Post Date: July 15, 2026]


Manager, Crystallization Science

View the Job Posting Here

Description:

About Varda
Low Earth orbit is open for business. Varda is accelerating the development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry capsules. Varda's W-Series vehicles are built, designed, and operated by Varda in-house, including the pharmaceutical processing payloads, the capsules, the C-PICA heat shields, and the satellite buses.

From life-saving pharmaceuticals to more powerful fiber optics, there is a world of products used on Earth today that can only be manufactured in space. Varda is accelerating innovation in the orbital economy by creating both the products and infrastructure needed so space can directly benefit life on Earth. Our mission is to expand the economic bounds of humankind.

Our team is uniquely suited to accomplishing this goal, with leadership and staff comprised of veterans from SpaceX, Blue Origin, major pharmaceutical companies and Silicon Valley. Varda was founded in January 2021 by Will Bruey and Delian Asparouhov with significant backing from world class investors including Khosla Ventures, Lux Capital, Founders Fund, Caffeinated Capital, General Catalyst, and Also Capital.

Varda is headquartered in El Segundo, California, where we have offices and a production facility where our vehicles, equipment, and materials are built, integrated, and tested. Varda also has offices in Washington, DC and Huntsville, AL.

Join Varda, and work to create a bustling in-space ecosystem.

About this Role
Our pharmaceutical team is looking for a highly motivated and effective Manager who will lead the Crystallization Screening Team towards our efforts in improving therapeutics with microgravity. This is an opportunity in an exciting area of growth for Varda, where you will get to shape Varda's biopharma culture and will play a significant role in establishing the low Earth orbit economy.

Responsibilities
•Oversee crystallization screening and characterization of molecules for microgravity opportunities across a diverse range of modalities including small molecules and biologics.
•Supporting the team in advancing the field of microgravity crystallizationt, while adopting best practices in drug substance development, including adoption of automation technologies to accelerate development timelines.
•Supporting and advancing collaborations with external partners, CROs, and vendors.
•Ensuring alignment of research and development activities, budgets, and timelines to company goals and initiatives, together with project organization and tracking to ensure projects deliverables meet timeline expectations.
•Effectively managing interfaces across the pharmaceutical development groups.

Basic Qualifications
•Ph. D, degree in Chemistry, Biochemistry, Chemical Engineering, Materials Science or related fields and 4+ years of relevant industry experience or M.S., degree in related fields and 8+ years of relevant industry experience.
•Hands-on experience with either polymorph screening of small molecules or crystallization of biologics.
•Strong foundation in materials science, organic chemistry, protein chemistry and/or physical biochemistry principles.
•Demonstrated ability to set technical direction and deliver results.
•Proficiency with data analysis tools (e.g., Excel, GraphPad Prism, Python, or R).
•Demonstrated ability to work independently with strong organizational skills.
•Excellent written and verbal communication skills.
•Alongside breadth, demonstrated depth of technical expertise and scientific leadership in at least one modality and aspect of drug substance development (analytical, crystallization, process engineering, or drug product development).
•Experience managing external partnerships.
•Exceptional organizational and project management capabilities.

Preferred Skills and Experience
•Ph. D, degree in Chemistry, Biochemistry, Chemical Engineering, Materials Science or related fields and 8+ years of relevant industry experience or M.S., degree in related fields and 12+ years of relevant industry experience.
•Experience in crystallography and relevant analytical techniques including XRPD, TGA, DSC, ED, cryo EM.
•2+ years of prior people-management experience.
•Track record of scientific achievement as demonstrated by publications in peer-reviewed journals and presentations at scientific conferences.
•Demonstrated expertise in new technology development (platform, modality, or process).
•Experience applying quality by design, or statistical process engineering methodologies in a research & development environment to ensure structured development strategies.
•Experience establishing and enforcing technical and programmatic standards.
•Exceptional communication ability with diverse technical and executive audiences.

Pay Range
•Salary range: $160,000 - $190,000/per year
•This role is on-site in El Segundo, CA
•Leveling and base salary is determined by job-related skills, education level, experience level, and job performance
•You will be eligible for incentives in the form of stock options and/or long-term cash awards

Benefits
Varda offers a comprehensive benefits package designed to support health, financial well-being, and a high-quality workplace experience. Below is an overview of what full-time employees receive (at this time, interns receive a subset of benefits):

Health & Wellness
•Flexible PTO policy + 12 paid holidays
•100% company-paid Medical, Dental, and Vision insurance plans for employees and dependents with FSA and employer-matched HSA options
•Voluntary accident, hospital, critical illness, and pet insurance
•$120/month wellness reimbursement for gym and fitness expenses
•12 weeks of parental leave (with supplemental disability leave for CA mothers)
•Family building, pregnancy, parenting and menopause benefits via Maven Clinic
•Sponsored One Medical memberships for employees and their dependents

Financial & Retirement
•Substantial incentive equity in a fully funded space start-up
•401(k) retirement plan with 6% employer match (immediately vested)
•$20/pay period cell phone reimbursement
•Relocation support for new hires, if needed

Workplace Experience & Perks
•Fully stocked kitchen with lunch provided daily and dinner provided twice weekly
•Company and team-bonding events, happy hours and mission-success celebrations
•Complimentary EV charging

ITAR Requirements
Varda, like all employers, must ensure that its employees working in the United States are lawfully authorized to work in the U.S. Additionally, our employees are exposed to and have access to certain export-controlled items. Because our employees are provided access to export-controlled items, our policy is to only hire “U.S. persons” who are permitted to have access to our technology without an export license.

"US person" means: U.S. citizen, U.S. lawful permanent resident, or protected individual as defined by 8 U.S.C. 1324b(a)(3) (i.e., individual admitted to the U.S. as a refugee or granted asylum).


[Post Date: July 13, 2026]


Postdoctoral Research Associate - AI-driven Lab Automation for Life Sciences

View the Job Posting Here

Description:

Brookhaven National Laboratory’s National Synchrotron Light Source II (NSLS-II) seeks a Postdoctoral Research Associate for AI-driven Lab Automation for Life Sciences for an on-site position in the Biological, Environmental and Planetary Science Division.

The aim of the position is to advance the frontiers of structural biology by developing AI-driven methods for improving crystal quality at scale. This role will enable new discoveries in life sciences and bio-technology relying on structural biology methods.

The ideal candidate would have a background and an interest in Biophysics, Biochemistry, Artificial Intelligence and Machine Learning.

Join a team of scientists at the leading macromolecular crystallography beamlines, the crystallization laboratory, the computing center and contribute to science projects at the interface between AI method development and large-scale research facilities.

Essential Duties and Responsibilities

  • Develop and implement AI-enabled laboratory-workflows for automated crystallization screening, optimization, and characterization integrating imaging, experimental metadata, and diffraction outcomes.

  • Design and deploy computer vision methods to detect and track crystal growth.

  • Develop closed-loop optimization approaches to recommend crystallization conditions and harvesting strategies based on experimental feedback.

  • Develop, train and integrate AI/ML models with laboratory automation systems, including crystallization robotics, liquid handlers, and imaging platforms.

  • Build scalable data pipelines linking experimental metadata, imaging data, and diffraction results for high-throughput analysis.

  • Evaluate model performance using experimental metrics and support deployment into user-facing workflows.

  • Collaborate with synchrotron beamline scientists and laboratory and crystallization staff.

  • Document methods and results, contribute to manuscripts and reports, and present the work at conferences.

  • Participate in interdisciplinary team science.

Required Knowledge, Skills, and Abilities

  • Ph.D. in computer science, bioinformatics, biophysics, applied mathematics, or related field.

  • Expertise in machine learning, computer vision, or image analysis.

  • Experience with data management and databases.

  • Experience working with Python, scientific software development, version control and collaborative code development, such as Git

  • Ability to work in interdisciplinary teams.

  • Strong publication record.

Preferred Knowledge, Skills, and Abilities

  • Experience with machine learning frameworks (PyTorch, TensorFlow, etc.) and integrating ML in a research lab facility.

  • Familiarity with lab automation or robotics.

  • Experience with black-box optimization, including active learning or Bayesian optimization.

  • Experience with imaging, time-series or high-dimensional data.

  • Exposure to crystallography or structural biology.

  • Experience with multimodal datasets and developing reproducible workflows.

  • Familiarity with experiment tracking and metadata capture.

Additional Information:

  • This position is a 2-year term, with the possibility of renewal contingent on performance and funding availability
  • Brookhaven Laboratory is committed to providing fair, equitable and competitive compensation. The full salary range for this position is $ $71,900-$119,000 / year. You will be placed at the level and salary commensurate with your experience. Salary offers will be commensurate with the final candidate’s qualification, education and experience and considered with the internal peer group
  • Candidates must have completed all degree requirements by the commencement of employment
  • BNL policy requires that after obtaining a PhD, eligible candidates for research associate appointments may not exceed a combined total of 5 years of relevant work experience as a post-doc and/or in an R&D position, excluding time associated with family planning, military service, illness or other life-changing events

Brookhaven National Laboratory is committed to employee success and we believe that a comprehensive employee benefits program is an important and meaningful part of the compensation employees receive. Review more information at BNL | Benefits Program

Brookhaven National Laboratory requires all non-badged personnel including visitors to produce a REAL-ID or REAL-ID compliant documentation to access Brookhaven National Laboratory – view more information at www.bnl.gov/real-id.  This is due to nationwide identification requirements for federal site access as required by the federal REAL ID Act.  Those not in possession of a REAL ID-compliant document will not be permitted to access the site which includes access to the Laboratory for interviews

As a U.S. Department of Energy laboratory, Brookhaven National Laboratory requires employees to obtain and maintain a DOE Uncleared Personal Identity Verification (UPIV) credential in accordance with Homeland Security Presidential Directive 12 (HSPD-12) requirements. The credentialing process is completed as part of onboarding and enables access to DOE facilities and information systems. As a condition of employment, the selected candidate must be able to obtain and maintain a UPIV credential. These requirements are established under DOE Order 206.2 Chg. 2, Identity, Credential, and Access Management (ICAM- Identity, Credential, and Access Management (ICAM)), and DOE Order 473.1A- Physical Protection Program- Physical Protection Program.

About Us

Brookhaven National Laboratory (www.bnl.gov) delivers discovery science and transformative technology to power and secure the nation’s future. Brookhaven Lab is a multidisciplinary laboratory with seven Nobel Prize-winning discoveries, 37 R&D 100 Awards, and more than 70 years of pioneering research. The Lab is primarily supported by the U.S. Department of Energy’s (DOE) Office of Science. Brookhaven Science Associates (BSA) operates and manages the Laboratory for DOE. BSA is a partnership between Battelle and The Research Foundation for the State University of New York on behalf of Stony Brook University. BSA salutes our veterans and active military members with careers that leverage the skills and unique experience they gained while serving our country, learn more at BNL | Opportunities for Veterans at Brookhaven National Laboratory.

Equal Opportunity/Affirmative Action Employer

Guided by our core values of integrity, responsibility, innovation, respect, and teamwork, Brookhaven Science Associates is an Equal Employment Opportunity Employer-Vets/Disabled. We are committed to fostering a respectful and collaborative environment that fuels scientific discovery. We consider all qualified applicants without regard to any characteristic protected by law. All qualified individuals are encouraged to apply. We ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.  *VEVRAA Federal Contractor

BSA employees are subject to restrictions related to participation in Foreign Government Talent Recruitment Programs, as defined and detailed in United States Department of Energy Order 486.1A. You will be asked to disclose any such participation at the time of hire for review by Brookhaven. The full text of the Order may be found at: https://www.directives.doe.gov/directives-documents/400-series/0486.1-BOrder-a/@@images/file


[Post Date: July 13, 2026]