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Crystallography related career opportunities, post docs and related positions in the crystallography community. If you wish to place your job opportunity on the Hampton Research website, submit the details to tech@hrmail.com.


Lab Product Manager (Protein Crystallization)

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Description:

Formulatrix, Inc. is looking to fill the role  of product manager for protein crystallization. You will be responsible for shaping the future of the protein crystallization business unit within Formulatrix, as well as aligning current and future technologies and software to the needs of our customers.

Product management requires a customer focused, hands-on, organized, and detail-oriented person able to work in a fast-paced environment. The ideal candidate will have a strong user-centered software design philosophy, excellent communication, cross-group collaboration and planning skills. Candidates must work well independently, with a global team and with customers.

Formulatrix requires hard work and dedication from its employees, and is committed to hiring only the best of the best. All support and management employees work 45 hour work weeks.

In return, Formulatrix offers a rewarding compensation package including base salary, bonuses, profit sharing, health and dental benefits, AFLAC supplemental insurance, a 401K retirement plan, a business casual work environment including Friday cookouts in the summer, and excellent growth opportunities.

Key Responsibilities

  • Take a leadership role in shaping the functionality and user experience of our protein crystallization software applications.
  • Prioritize and define features by working with customers, support and sales team.
  • Provide a vision for user experience and work with UX designers to detail the new features.
  • Oversee and support our development team in the implementation of new functionalities.
  • Support customers with protein crystallization product questions and requests.
  • Some domestic and international travel may be required.

Required Qualifications

  • Passion for customer satisfaction and great, high quality products.
  • BS + 5 years experience or MS + 3 years experience or PhD in a scientific field.
  • At least 3 years of experience in a laboratory setting (a graduate experience will be considered)
  • Strong leadership and verbal/written communication skills.
  • Excellent prioritization, organizational and planning skills.
  • Ability to learn and quickly adapt to a constantly changing environment.
  • Ability to work with an offshore team.

Preferred Qualifications

  • Experience with protein crystallography.
  • Experience with mammalian cell cultures.
  • Experience with commercially available laboratory automation.
  • Experience with graphical user interface design.
  • Experience with the entire software development lifecycle.

How to Apply

** RESUMES SUBMITTED WITHOUT THE INFORMATION REQUESTED BELOW WILL NOT BE CONSIDERED **

To be considered for this position, please email jobs@formulatrix.com with the words "Product Manager - Protein Crystallography" in the subject line. You must include a copy of your resume, (Word, PDF, plain text or RTF only) and answer the following five questions in the body of your email:

  • What attracts you to this job and how do you feel your skill sets will complement the position?
  • What are your salary expectations?
  • When can you start?
  • Are you authorized to work in the United States?
  • Will you now or in the future require sponsorship for employment visa status (e.g., H-1B visa status)?

** NO RECRUITERS OR AGENCIES **


[Post Date: September 21, 2020]


Postdoctoral Position at the NIH on Structural Biology of Noncoding RNAs and RNPs

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Description:

Position Description: A postdoctoral position is available in the Structural Biology of Noncoding RNAs and Ribonucleoproteins Section, Laboratory of Molecular Biology (LMB), NIDDK, in NIH’s vibrant main campus in Bethesda, MD near Washington DC. The lab addresses a widening gap between the accelerated discovery and functional description of the noncoding transcriptome, and the lack of structural and mechanistic understanding of complex noncoding RNAs and RNPs. We seek a new member to join our diverse group to study gene-regulatory riboswitches, highly structured viral RNAs, long noncoding and circular RNAs and their RNP complexes. See https://www-mslmb.niddk.nih.gov/zhang/zhanglab.html for details.

The lab is part of the Earl Stadtman Investigator program for high-risk, high-impact research at the NIH intramural program consisting of 1100 labs. The lab has dedicated access to complete suites of state-of-the-art equipment in structural biology (Mosquito, Dragonfly, Rock Imager, Akta Pures, FSEC, etc., and regular synchrotron access for X-ray crystallography; Titan Krios and Glacios for single-particle Cryo-EM; SAXS, AFM, NMR, etc), cutting-edge biochemistry, biophysics (ITC, DSC, SPR, BLI, AUC, DLS, SEC-MALS, CD, fluorescence, thermophoresis, iSCAMS, etc), fermentation, advanced mass spec, genomics and sequencing, and proteomics core facilities with hands-on training or service by PhD-level staff scientists.

We apply innovative technologies to study RNA and RNP structure, dynamics, and interactions, such as rational RNA design and engineering, RNA cryo-EM, XFEL, ultrafast SAXS/WAXS, single-molecule fluorescence, crosslinking-mass spec., etc. Ongoing projects include structural and mechanistic elucidations of the T-box riboswitches in bacteria and Gcn2 kinase in eukaryotes in cellular stress responses. A second area addresses how numerous viral and host structured noncoding RNAs differentially manipulate immune protein activities such as PKR. For details refer to recent publications:

Suddala K.C & Zhang, J. (2019) High-affinity recognition of specific tRNAs by an mRNA anticodon-binding groove, Nat. Struct. & Mol. Biol., 26, 1114–1122.

Li S. et al., & Zhang, J. (2019) Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions, Nat. Struct. & Mol. Biol., 26, 1094–1105.

Hood, I.V. et al., & Zhang, J. (2019). Crystal structure of an Adenovirus Virus-Associated RNA, Nat. Commun. 10:2871

Incoming fellows are also encouraged to bring your own ideas that you could develop into research programs that you can then take to your independent PI positions. The NIH, NIDDK, and LMB are committed to the continued education and career development of trainees through numerous courses and workshops offered by OITE, FAES, and NIDDK.

Requirements: Interested candidates must have received (or be expecting) a Ph.D. or M.D. within the past five years in molecular biology, structural biology, biochemistry, cell biology, or a related discipline, have excellent oral and written communication skills, and be strongly self-motivated to participate in and design innovative and rigorous research projects. Prior experiences in structural biology are not required.

To apply: Please email a cover letter indicating preferred start date, CV, a brief summary of research interests, accomplishments, and career goals, and names and contact information for at least three references to: Dr. Jinwei Zhang, Email: jinwei.zhang@nih.gov. The NIH is dedicated to building a diverse community in its training and employment programs. DHHS/NIH is an Equal Opportunity Employer.


[Post Date: September 18, 2020]


Position Available - Protein Sciences Specialist

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Description:

The Harvard Medical School Therapeutics Translation is seeking an individual to join its scientific team, in support of our drug discovery effort against emerging pathogens.  The candidate would work collaboratively with several labs at HMS and the affiliated hospitals as a key contributor for ongoing structural biology efforts assisting corona virus related drug discovery programs. This will include solving novel structures of both viral and host proteins and routine co-structures of small and large molecules with their target proteins.  The successful candidate will engage in all aspects of structural biology including protein production, crystallization and structure determination.  The position will be part of an interdisciplinary team, working with design chemists, biochemists, virologists and pharmacologists across several ongoing projects. These team interactions will be both in person, and within the virtual environment.

For more information on the position as well as how to apply, please visit https://bcmp.hms.harvard.edu/news/position-available-protein-sciences-specialist


[Post Date: September 18, 2020]


Job Vacancy: Postdoctoral research fellow position available in Therapeutics Discovery Division at MD Anderson Cancer Center

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Description:

A postdoctoral position is currently available in the Structural Chemistry group, part of the Institute for Applied Cancer Science (IACS) within the Therapeutics Discovery Division of MD Anderson Cancer Center. Our mission is to integrate novel biological insights with drug discovery expertise to accelerate the development of innovative, targeted, small-molecule therapeutics for unmet medical needs. Our work is conducted in a team science environment that brings together excellence in both academic and pharmaceutical discovery, as evidenced by recent publications.

We are seeking a highly motivated individual with a strong background in structural biology, including protein expression and purification, protein crystallization, and X-ray crystallography structure determination. Experience with cryo-EM structure determination and/or structure determination of membrane proteins is not required, but would be advantageous. We are seeking only the most dedicated individuals who will join us in our quest to discover, develop and deliver more effective treatments to our patients. This is a unique opportunity to participate in project-driven drug discovery research within a highly respected academic and clinical setting.

Interested individuals should apply via the Postdoc Jobs website. 

https://www.postdocjobs.com/posting/7069370


[Post Date: September 15, 2020]


Postdoctoral position available at the Institute of Cancer Research, London UK

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Description:

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top five cancer centres globally.

The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.

The Cancer Research UK Cancer Therapeutics Unit (CTU), within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The CTU’s exciting goal is to discover high quality small molecule drug candidates and to progress these to clinical trial. All the scientific disciplines are in place to make this possible, including medicinal chemistry, biology, structural biology, assay scientists, drug metabolism and clinical specialists.

A postdoctoral position is available in Dr Rob van Montfort’s Hit Discovery and Structural Design Team within the CTU in Sutton. The Post-doc will be involved in X-ray crystallography, fragment-based screening and structure-based drug design and will be responsible for protein expression, purification, crystallisation, structure determination and structural analysis of protein-ligand complexes from one of the CTU’s drug discovery programmes. The successful candidate will also be part of the Division of Structural Biology, located in Chelsea, in which the structural biologists in Dr van Montfort’s team are embedded, and will have access to state-of-the art crystallisation facilities, in-house X-ray sources and excellent access to synchrotrons. The successful candidate will interact closely with the biology, computational chemistry and medicinal chemistry teams at the CTU, and will therefore be expected to work across the two sites in Chelsea, London and Sutton, Surrey.

Applicants must have a PhD in a biological or physical science, and experience in macromolecular crystallography (to include protein biochemistry, protein crystallisation and protein crystallography). Experience in molecular biology, protein expression in insect cells, structure-based drug design, and/or biophysics will be an advantage.

The starting salary for the position will be in the range £32,844 to £40,137 p.a. inclusive (based on previous post-doctoral experience) and the post is offered on a fixed term contract of 1 year.


[Post Date: September 11, 2020]


Postdoc position in membrane protein strucrual biology at Case Western Reserve University

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Description:

The laboratory of Nami Tajima at Case Western Reserve University School of Medicine is seeking a highly motivated and creative individual with expertise in structural biology and molecular neuroscience/electrophysiology to elucidate the molecular mechanism of ligand-gated ion channel signaling complexes. Our research interests are focused on (i) understanding the regulatory mechanisms of ion channels involved in basic brain functions and neurological diseases, (ii) dissecting the signaling networks/ protein-protein interactions in the context of synaptic signaling, and (iii) structure-based drug discovery. We take an interdisciplinary approach and combined methods from Cryo-EM, X-ray crystallography, electrophysiology, molecular and cellular biology, and biochemistry/biophysics. Case Western Reserve University is equipped with state-of-art structural biology facility including screening microscopes, and a Titan Krios with a K3 camera.

The successful candidate for the postdoctoral researcher must have a recent Ph.D. obtained within three years (or being in the process of completing one) in a relevant field with a demonstrated track record of productive research. Expertise in one or more of the following areas; biochemistry, biophysics, protein expression and purification, cryo-EM, X-ray crystallography, electrophysiology, neuroscience, cell biology, mass spectrometry, and invitro and in vivo fluorescence imaging. Interested applicants should submit (1) a cover letter describing research interests and career goals; (2) a CV; and (3) contact information for 2-3 references by email to Nami Tajima at nxt193@case.edu.

https://physiology.case.edu/people/faculty/nami-tajima/


[Post Date: September 15, 2020]


Postdoc position in structural virology, BNITM, Hamburg, Germany

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Description:

I am recruiting a new postdoc to support a collaborative project between CSSB/HPI (Grünewald lab), EMBL Grenoble (Cusack lab) and BNITM aiming at solving structures of viral polymerase proteins.

Candidate profile:

  • Completed PhD in the field of biochemistry and/or structural biology
  • Strong expertise in protein expression, protein purification and biochemical assays
  • Fluent oral and written English
  • Excellent organizational skills and ability to plan and execute experiments independently and flexibly
  • Strong team spirit and excellent communication skills
  • Creative mindset and strong problem-solving capabilities
  • Experience with working in the radioactivity lab is a plus
  • Experience with common model building and structure refinement programs (Coot, Phenix, CCP4) is beneficial
  • Proficiency in commonly used laboratory software is expected (Office, PyMOL, Chimera etc.)

We offer an interesting and challenging project in a modern research institution and within a stimulating international collaboration, competitive salary included. Hamburg is a great place to live and for structural biology research. My team is open-minded, motivated and highly supportive. More about our work can be found here: https://www.bnitm.de/en/research/research-groups/molecular-biology-and-immunology/virology-department/biochemistry-and-structural-biology/

The position is only open for 20 months (full-time equivalent) and the scientist should start as soon as possible BUT the project is up and running.

Ready to join? -Apply! --> https://jobs.bnitm.de/Postdoc-mwd-full-time-or-part-time-EG-13-TV-AVH--eng-j100.html


[Post Date: September 11, 2020]


Postdoc Dana-Farber Cancer Institute and Harvard Medical School, Boston, USA

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Description:

The collaborative Jia-huai Wang and Ellis Reinherz labs at Dana-Farber Cancer Institute and Harvard Medical School are recruiting a postdoctoral fellow to study structural immunology. We use interdisciplinary approaches at the interface of structural, molecular mechanism of cellular immunity with the aim of translating these insights into immunotherapy. Specific research directions include structural and molecular studies of T cell development. The laboratory provides a full access to cutting-edge techniques in molecular biology, protein chemistry, NMR and protein crystallography.

Highly-motivated candidates with a recent PhD or MD/PhD in structural biology and significant experience in molecular biology, biochemistry and immunology are encouraged to apply. Skills in molecular cloning, protein chemistry and crystallography are essential. Candidates should have a publication record in peer-reviewed journals. We are seeking a candidate with excellent writing and communication skills, able to work independently but also effectively with other lab members. Applicants should include a short statement of research goals, CV and three references with their application.

Please contact Dr. Jia-huai Wang at jwang@crystal.harvard.edu.

 


[Post Date: September 10, 2020]


Postdoctoral researcher in Structural bioinformatics, Manstein lab, Dept. Structural Biochemistry, Hannover Medical School (MHH), Germany

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Description:

The project focuses on molecular machines and their role in disease processes. We are looking for a postdoctoral researcher who will support us primarily with molecular dynamics simulations of ligand-induced changes in the conformational dynamics of molecular machines and their complexes. Knowledge in 3D structure determination of protein-protein and protein-ligand complexes is desired.

Our laboratory has state-of-the-art facilities for protein purification, crystallization, imaging and in situ X-ray diffraction of crystals, and dedicated computational resources for structural biology and bioinformatics.

Applicants are expected to have: (1) PhD degree, (2) demonstrated competency in structural bioinformatics, (3) expertise in protein crystallization, X-ray structure determination and structural analysis, (4) willingness to work as part of a collaborative, multidisciplinary team.

Starting date: 1st November 2020 onwards. Please indicate your availability.

Review of applications will begin immediately and continue until the position is filled.

Application: The application should include (compiled in one .pdf file):
(1) a Letter of motivation describing your key expertise and research interests, and
(2) CV with list of publications and contact information for 1-2 referees (or letter of recommendation).

Applications and informal inquiries should be e-mailed to Schille.Joanna@mh-hannover.de with the subject “PDP- Structural bioinformatics”.


[Post Date: September 10, 2020]


Post-doctoral researcher in Structural biology, Salminen lab, Structural Bioinformatics Laboratory, Abo Akademi University, Turku, Finland

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Description:

The project focuses on two medically relevant cell-surface receptors and their multifaceted interactions in inflammation and cancer. The group seeks for a post-doctoral researcher for 3D structure determination of protein-protein and protein-ligand complexes enabling rational development of anti-inflammatory and anti-cancer agents as well as improved tools for imaging inflammation.

Our laboratory has state-of-the-art facilities for protein purification, crystallization, imaging and in situ X-ray diffraction of crystals, and computational resources for structural biology and bioinformatics (https://www.abo.fi/en/structural-bioinformatics-laboratory/).

Applicants are expected to have: (1) PhD degree, (2) demonstrated competency in protein expression and purification strategies using bacterial, insect, and mammalian hosts, (3) expertise in protein crystallization, X-ray structure determination and structural analysis, (4) experience in biophysical methods for analysis of protein interactions, and (5) willingness to work as part of a collaborative, multidisciplinary team.

Starting date: As soon as possible. Please indicate approximate starting date.

Review of applications will begin immediately and continue until the position is filled.

Application: The application should include (compiled in one .pdf file):
(1) a Letter of motivation describing your key expertise and research interests, and
(2) CV with list of publications and contact information for 1-2 referees (or letter of recommendation).
Applications and informal inquiries should be e-mailed to tiina.naumi(at)gmail.com with a subject “Postdoctoral position”.


[Post Date: September 9, 2020]


Postdoc Membrane Structural and Functional Biology – Caffrey Lab Trinity College Dublin, Ireland

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Description:

Post Summary  The Membrane Structural and Functional Biology group seeks to solve the structure of medically important membrane proteins for use in structure/function studies and for structure-based therapeutics development. Target proteins are involved in communicable and non-communicable diseases.

An exciting postdoctoral research position is available in the Group. We are looking for a highly motivated, creative and hardworking individual with experience in biochemistry and molecular biology to join our multidisciplinary team at Trinity in a lab that offers superb facilities. Individuals interested in moving into the membrane protein field are encouraged to apply.

Person Specification  The candidate must have a Ph.D. in biochemistry, biophysics, molecular biology or a related field. Demonstrated success in all aspects of molecular biology, recombinant protein production, purification, and functional characterization is required. Experience with membrane protein over-expression, crystallization, and structure-function studies is desirable. The candidate should be a highly motivated and creative individual who enjoys working as part of a collaborative, multidisciplinary team. Strong leadership, communication and teaching skills are decided assets. A willingness and freedom to travel worldwide on short-term projects is expected.

Salary  €38,631 - €45,942 per annum depending on experience

Closing Date  Until the position is filled

Principal Investigator Prof. Martin Caffrey 

https://www.tcd.ie/Biochemistry/research/caffrey/  

Application Procedure  Candidates are asked to submit a letter detailing education, training and laboratory experience. In the letter, the candidate should outline why they feel they are suitable for the position in an interdisciplinary group that will involve extensive interaction with collaborators and data collection at facilities around the globe. The letter of application must be accompanied by a comprehensive CV to include the names and contact details of two referees (email addresses and phone numbers to be provided). At least one referee should be an individual the candidate has worked with and who has agreed to provide a letter of reference on the candidate’s behalf. 

Applications should be emailed to: msfb789@gmail.com  


[Post Date: September 9, 2020]


Postdoctoral Fellowship in Structural Biology at Uppsala University

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Description:

Opening for a postdoctoral fellow in the Department of Cell and Molecular Biology, Uppsala University.

The project aims to study the structure and function of metal-responsive transcription factors. The successful candidate should have an excellent track record and experience in X-ray crystallography as well as protein expression and purification. Experience of complementary techniques in biochemistry and biophysics would be a benefit.

For more information about the position and how to apply please see the job post on ResearchGate at the link.


[Post Date: September 8, 2020]


Beamline Scientist, I24

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Description:

We are looking for a beamline scientist to join the team at I24, Diamond. We are looking for someone with experience, or a strong interest, in microfocus MX and/or serial crystallography who is enthusiastic about helping us to develop new approaches and deliver them to the user community.  For more details and to apply please see t he link.  The closing date is Sunday, September 27, 2020.


[Post Date: September 8, 2020]


Principal/Sr. Scientist, Structural Biology

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Description:

FogPharma is looking for a Principal/Senior Scientist to contribute to the development of helical peptides. We are seeking a highly motivated X-ray crystallographer who will play an integral part of our structure-based drug design effort on multiple programs.  Please apply through the link.


[Post Date: September 8, 2020]


Postdoctoral Position (DNA Repair) – University of Florida, Department of Biochemistry and Molecular Biology

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Description:


The Caglayan lab in the Department of Biochemistry and Molecular Biology, University of Florida seek an outstanding individual with Ph.D. training in biochemistry and/or structural biology to study the DNA repair. The NIH-funded research project will focus on studyinggenome stability, DNA repair, and DNA damage processing (Caglayan M. 2020, Nuc. Acids, Res.; Caglayan M. 2020, DNA Repair; Caglayan M. 2019, J. Mol. Biol., Caglayan M. et al., 2018 Nat. Comm., Caglayan M. et al., 2017 Nat. Comm., Caglayan M. et al., 2014 Nat. Struc. Mol. Biol.) The Caglayan group is in both the Department of Biochemistry and Molecular Biology, and UF Health Cancer Center with investigators renowned for their contributions to the area of biochemistry and cancer biology. The lab utilizes a multi-disciplinary approach to investigate complex biological questions using X-ray structure (structure-function studies), biochemistry, enzymology, and molecular biology.

Minimum Requirements
PhD in a related discipline


Preferred Qualifications
• Experience in purifying recombinant proteins by affinity chromatography methods
(IEX, HIC, SEC) is required.
• Experience in protein-protein and protein-DNA interaction assays (ITC, SPR with Octet
and/or Biacore systems) is essential.
• Experience working with purified proteins and biochemical assays
• Prior experience in enzymology is an advantage (for biochemists).
• Experience in designing constructs for recombinant protein production of
crystallographic studies (X-ray crystallography and/or Cryo-EM).
• Previous working experience with evidence of experimental skills and publication
record with DNA repair is not required, but preferred.


Advertised Salary
The salary for this position is commensurate with experience as determined by NIH guidelines.


How to apply?
To apply, please send Curriculum Vitae, a cover letter, and contact information for three (3)
letters of recommendations to Dr. Melike Caglayan (caglayanm@ufl.edu).

 Download PDF

[Post Date: September 2, 2020]


Description:

A postdoctoral fellowship position is available in the Tsai laboratory at Baylor College of Medicine to investigate the 3D structure, mechanism, and function of ATP-dependent protein quality control machines and related stress-response proteins (Proc. Natl. Acad. Sci. USA 2016; Cell Rep. 2019; J. Mol. Biol. 2019; eLife 2020). Applicants with a Ph.D. in molecular biology, biochemistry or enzymology are encouraged to apply. Demonstrated experience with methods used to express and purify proteins is essential; experience with PCR cloning and site-directed mutagenesis is desired. Prior experience in enzymology or working with a model organism (e.g. bacteria, yeast, worms) is an advantage. The successful applicant will be highly motivated and possess excellent communication skills. S/he will join a multi-disciplinary team that uses systems biology methods to address questions of high biomedical importance. Salary is pegged to the current NIH scale and is in addition to a generous fringe benefit package. To apply, please send a cover letter with research interests and experiences, your current CV, and contact information for three referees to Dr. Francis Tsai (ftsai@bcm.edu).

  • Experience with common statistical methods for data analysis is essential. 
  • Experience with PCR cloning and IEX, HIC, SEC chromatography is required. 
  • Prior experience in enzymology is an advantage (for biochemists). 
  • Prior experience with model organisms is an advantage (for molecular biologists). 
  • Applicants must be able to work independently and as a member of a team.

Applicants with a recent Ph.D. in biological sciences, pharmacology, chemistry, microbiology, or biophysics will be considered if they meet the required criteria. Essential experience is fulfilled by having one first (or co-first) author publication in a reputable peer-reviewed journal. 


[Post Date: September 1, 2020]


Postdoctoral Position

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Description:

Understanding enzyme catalysis by filming enzymes at atomic/fs resolution

Postdoctoral Position

Enzymes are the best performing catalysts on Earth, yet the details of their function — for example what role dynamics play or not in chemical rearrangements — remain a source of debate. New x-ray free electron laser (XFEL) technology allows us to directly image proteins at the time and length-scales (atoms/fs) on which chemistry occurs, making it possible to directly study enzyme catalyzed reactions via imaging. The photobiology group led by TJ Lane at CFEL seeks a postdoctoral candidate conduct this work on naturally occurring and man-made photoenzyme systems.

As the ideal candidate, you will have the following key attributes:

  • A doctoral degree in physics, chemistry, biochemistry, or a related field
  • Excellent wet-lab skills, with knowledge of how to produce, purify, and crystallize proteins
  • A basic familiarity with serial femtosecond crystallography and XFELs
  • Basic computational skills including unix-style environments, python/matlab/similar
  • The ability to drive your work independently and show initiative

And you will be excited to take on the following responsibilities:

  • Design of experiments, including new hardware and software when necessary
  • Organizing and leading teams of 2-20 people to conduct XFEL experiments
  • Preparation of protein crystal samples and wet lab bio/chemistry
  • Interpretation and analysis of experimental results
  • Helping to foster an environment conducive to collaboration, learning, growth, and fun

The position offers a chance to work in a world-leading center in the midst of some of the pioneers of the x-ray laser field. CFEL, DESY, and the broader Science City Bahrenfeld offer an interdisciplinary, collaborative, welcoming, and energizing environment backed by excellently equipped labs, computational and engineering support, and a mindset that no problem is too big to tackle. You will bring your initiative and energy to use these resources and this environment to do great science.

Available immediately is a two year contract with the possibility to extend to three years, with a competitive salary and the opportunity to work and live in the beautiful and vibrant city of Hamburg, Germany.

For more details or to apply, write directly to TJ Lane and provide a CV and short introduction or cover letter.

Understanding and controlling enzyme catalysis through design of photoactive compounds

Postdoctoral Position

Enzymes are the best known catalysts on Earth. The photobiology group led by TJ Lane at CFEL seeks a postdoctoral candidate to develop new chemical technology that will turn regular enzymes into photoenzymes, where the reaction requires light. This enables spatio-temporal control of enzyme chemistry in the biological context, as we can use a laser to initiate the reaction — opening opportunities for learning about how enzymes do their magic both in vitro and in vivo.

As the ideal candidate, you will have the following key attributes:

  • A doctoral degree in chemistry, biochemistry, or a related field
  • Experience working with proteins and biochemical assays
  • Chemical intuition and basic knowledge of organic chemistry and synthesis
  • An undergraduate-level or higher understanding of quantum mechanical principles and how they relate to photochemical behavior
  • The ability to drive your work independently and show initiative

And you will be excited to take on the following responsibilities:

  • Identifying the most important scientific questions in the field of enzyme catalysis
  • Design of experiments, including new hardware and software when necessary
  • Develop new biochemical assays
  • Develop high-throughput screens for new photo-active chemical matter
  • Collaborate with computational chemists to develop new compound designs
  • Helping to foster an environment conducive to collaboration, learning, growth, and fun

The position offers a chance to work in a world-leading center in the midst of some of the pioneers of the x-ray laser field. CFEL, DESY, and the broader Science City Bahrenfeld offer an interdisciplinary, collaborative, welcoming, and energizing environment backed by excellently equipped labs, computational and engineering support, and a mindset that no problem is too big to tackle. You will bring your initiative and energy to use these resources and this environment to do great science.

Available immediately is a two year contract with the possibility to extend to three years, with a competitive salary and the opportunity to work and live in the beautiful and vibrant city of Hamburg, Germany.

For more details or to apply, write directly to TJ Lane thomas.lane@desy.ed and provide a CV and short introduction or cover letter.


[Post Date: August 31, 2020]


Postdoctoral Position

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Description:

Understanding how proteins move by through multi-crystal analysis

Postdoctoral Position

We know proteins make use of long-range motions to perform the essential functions of life: transmit signals, conduct chemistry, and mechanically alter the environment, but how proteins accomplish these amazing tasks remains unexplained at the atomic level. Experimentally measuring these long-range motions at atomic detail has been a challenge. Recently, our group had success in doing this for the main protease (Mpro) from SARS-COV-2, the virus behind the COVID pandemic. Many datasets on COVID and non-COVID proteins have been collected, but new methods are necessary to investigate and extract information about protein motions in these data — we seek a computational scientist to drive this work.

As the ideal candidate, you will have the following key attributes:

  • A doctoral degree in physics, biophysics, computer science, or a related field
  • Excellent computational skills, including python and modern data science methods
  • Capabilities in computational crystallography (serial crystallography a bonus but not required)
  • Knowledge of the principles of protein structure and function
  • The ability to drive your work independently and show initiative

And you will be excited to take on the following responsibilities:

  • Writing software and scripting to perform data analysis on a daily basis
  • Working with large, rich crystallographic datasets from synchrotrons and XFELs
  • Analysis/interpretation of experimental data and results
  • Helping to foster an environment conducive to collaboration, learning, growth, and fun

The position offers a chance to work in a world-leading center in the midst of some of the pioneers of the x-ray laser field. CFEL, DESY, and the broader Science City Bahrenfeld offer an interdisciplinary, collaborative, welcoming, and energizing environment backed by excellently equipped labs, computational and engineering support, and a mindset that no problem is too big to tackle. You will bring your initiative and energy to use these resources and this environment to do great science.

Available immediately is a two year contract with the possibility to extend to three years, with a competitive salary and the opportunity to work and live in the beautiful and vibrant city of Hamburg, Germany.

For more details or to apply, write directly to TJ Lane thomas.lane@desy.de and provide a CV and short introduction or cover letter.


[Post Date: August 31, 2020]


Scientist, Structural Biology

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Description:

TITLE:                  Scientist, Structural Biology

REPORTS TO:     Principal Scientist, Head of Structural Biology

LOCATION:        Cambridge, MA

About Foghorn

Through its Gene Traffic Control™ Product Platform, Foghorn® Therapeutics is discovering and developing an unprecedented class of medicines targeting diseases with genetically determined dependencies in the chromatin regulatory system. The Company, currently pre-clinical stage, is rapidly advancing over 10 programs across a wide range of cancers and is beginning to explore other diseases.

The chromatin regulatory system orchestrates the movement of molecules that turn genes on and off. Disease dependencies associated with chromatin dysregulation are estimated to impact approximately 2.5 million cancer patients in G7 countries and chromatin dysregulation is further implicated in neurological, autoimmune, and other serious diseases. Foghorn’s proprietary Gene Traffic Control Product Platform is based on the Company’s unique insights into the chromatin regulatory system and enables highly scalable drug discovery and development efforts.

Foghorn, a Flagship Pioneering® company, was founded in 2016 by Cigall Kadoch, Ph.D., Gerald Crabtree, M.D., and Doug Cole, M.D., of Flagship Pioneering. Learn more about Foghorn at www.foghorntx.com.

POSITION DESCRIPTION

We are seeking a highly skilled and motivated structural biologist to become an integral member of the Foghorn team. This person will contribute to our goal of developing transformative therapeutics by planning and carrying out structural characterization of crucial drug targets. The main focus of this role will be protein crystallography but will require a willingness to find new ways to think about scientific challenges. We need someone who is passionate, driven, and ambitious to help us achieve our goal of improving patients’ lives.

 

Responsibilities include:

  • Collaborating with colleagues in biochemistry, biology, and chemistry to develop structural biology strategy.
  • Designing biophysics-grade protein constructs and assisting in the optimization of purification protocols.
  • Crystallization, X-ray structure determination, and analysis of important drug targets.
  • Providing regular updates to cross-functional teams and helping guide structure-based compound design in close collaboration with medicinal and computational chemists.
  • Participating in the management of collaborations with contract research organizations (CROs) and academic partners.

 

QUALIFICATIONS

  • PhD in Structural Biology, Biophysics, Biochemistry or a closely related field, with a background in chemistry.
  • Demonstrated competency in protein construct design and expression and purification strategies using bacterial, insect, and mammalian hosts. Experience with multi-protein complexes is a plus.
  • Deep expertise in protein crystallization and X-ray structure determination of protein-ligand complexes.
  • Extensive knowledge of protein structure and function, with the ability to articulately communicate structural information to a broad audience.
  • Experience with other structural techniques (e.g. electron microscopy, small-angle X-ray scattering) is strongly preferred.
  • Excellent time management and communication skills.
  • Ability to work in a fast-paced, team-driven environment, with a collaborative and proactive attitude.


[Post Date: August 31, 2020]


Protein Scientist Crystallographer

View the Job Posting Here

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Description:

Exscientia is at the forefront of Artificial Intelligence (AI) driven drug discovery and the only company to have designed drug molecules by AI that are in clinical studies. Our mission is to revolutionise the pharmaceutical industry so that patients get faster access to life-saving drugs. Exscientia’s world-class leadership in AI-driven drug discovery has been recognised by partnerships with major pharmaceutical companies, joint ventures with biotech and technology companies and multiple investment rounds by top-tier investors. Exscientia is collectively working to build a cutting-edge future and we’re looking for like-minded individuals to join our journey.
 
Following multiple high-profile partnerships and our most recent Series C fundraise we are now adding a Protein Scientist/Crystallographer to our team.   The Protein Sciences team is part of Discovery Biology at Exscientia and is responsible for enabling small-molecule therapeutic projects by providing GPCR biology, protein production, biophysical and crystallographic capabilities. The team works on diverse target classes to support the transformative efficiency improvements in clinical candidate discovery demonstrated with our systems.  This position is for an experienced scientist specialising in X-ray crystallography, protein expression and purification to join the team and support the discovery of new therapeutic molecules. 
 
We are looking for an excellent Protein Scientist/Crystallographer to add value by being responsible for the crystallization and the structure determination of protein-small molecule complexes by x-ray crystallography. The work will include protein production for structural purposes, crystallization, X-ray data collection, structure determination, and analysis.

What will you be doing in this role?

    • Performing high throughput crystallization experiments on multiple protein targets with and without ligands.
    • Optimizing the initial crystallisation hits to obtain stable reproducible crystal systems.
    • Implementing established techniques of crystal manipulation including ligand soaking, crystal cryo-protection and harvesting.
    • Regular use of synchrotron facilities to execute standard x-ray data collection.
    • X-ray fragment screening experiments within the Diamond XChem pipeline.
    • Expression of proteins in heterologous systems such as E. coli, insect and mammalian cellsas required.
    • Purifying recombinant proteins by affinity chromatography methods.
    • Analysing recombinant proteins.
    • Bringing attention to detail including good record keeping
    • You will author high quality reports and data summaries.
    • Communicate updates to projects.
    • Representing Discovery Biology at scientific meetings.
    • Working to the highest scientific standards under the direction of the Head of Crystallography.

What will you bring to the role?

      • Experience with high throughput crystallisation methods for screening using robotics.
      • Know-how of strategy design for crystal conditions optimization.
      • Skill in crystal manipulation, including soaking, cryoprotection, crystal harvesting.
      • Experience in synchrotron source X-ray diffraction experiments, data collection optimization and beamtime preparation.
      • Proficiency with X-ray data processing, structure solution and refinement.
      • Knowledge of ligand chemical restraints definition and ligand structure refinement.
      • Experience in protein purification and analysis including affinity, ion exchange and size exclusion chromatography, SDS-PAGE and Western blotting and the use of FPLC systems
      • Excellent interpersonal intelligence
      • A demonstrable analytical approach to problem solving
      • The ability to work as part of a team
      • The successful candidate will possess a minimum of a strong honours degree plus either a postgraduate qualification up to a PhD degree or proven industry laboratory experience in the life sciences.

Desirable Experience

    • Understanding of all crystallographic methods (e.g. microbatch)
    • Comprehension of others structural biology techniques (e.g. SAXS and Electron Microscopy).
    • Experience in cell culturing techniques, ideally in both mammalian and insect cell lines.
    • Experience in designing constructs for recombinant protein production of crystallographic targets.
    • Previous work experience in an industrial environment. 

What will you get from us?

    • Making a positive contribution to patients by revolutionising the pharmaceutical industry through AI driven discovery
    • Joining a scaling AI organisation with world class technical and scientific leaders
    • An opportunity to grow your career with us as we grow our organisation
    • We offer a highly competitive compensation to support our employees as we continue to grow and thrive
    • The opportunity to join an inclusive, collaborative and intellectually stimulating culture
    • Working in brand new, state of the art laboratories
    • Modern offices with fantastic free food on offer


[Post Date: August 25, 2020]


Postdoctoral Fellowship - High-resolution structure and function of the multi-layered kidney slit diaphragm

View the Job Posting Here

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Description:

About this position

The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy).

The research group of Matthias Wilmanns has a long-standing record in structural biology on research themes that are of medical relevance. Most of our projects require the combined use of different structural biology methods including X-ray crystallography and cryo-electron microscopy, generally followed by functional experiments.

Your role

Project Outline: Ultrafiltration is a key function to maintain body homeostasis, and a major target of hereditary kidney diseases. The slit diaphragm presents the most outer kidney filtration barrier and is of paramount interest to understand the mechanism of kidney filtration both in the healthy human body as well as in patients suffering from its deregulation. We aim to determine the molecular architecture of the underlying protein components and their interactions at high resolution. In this project we will closely interact with an international leading team in the field of kidney research the from University Medical Center Hamburg-Eppendorf (Tobias B. Huber) aiming to directly translate the structural biology work to a better understanding of kidney filtration and kidney disease.

You have

   A PhD in a relevant field

   Proven record of scientific accomplishments

   Previously demonstrated expertise in high-resolution structural biology and biophysical approaches including sample preparation (molecular biology, protein purification)

   Scientific ambition

   International experience

   Openness and interest for interdisciplinary work in collaboration with medical researchers

   Excellent communication skills

You might also have

Additional expertise in biochemistry (in vitro and cell-based assays) and cell biology (including imaging) would be advantageous.

Why join us

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprises from a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including your family and the availability of an excellent child care facility on campus. EMBL has a large thriving community of bioinformaticians, working in close collaboration with experimental scientists and with strong links to other local scientists and institutions.

What else you need to know

We are Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1600 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research.

Informal inquiries should be sent to: matthias.wilmanns@embl.org.

Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

Please apply online through: www.embl.org/jobs


[Post Date: August 25, 2020]


Open Positions in Neutron Scattering at Oak Ridge National Laboratory

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Description:

We currently have four staff scientist job openings in our organization, below are the job posting titles along with links to the full position descriptions. Please note job applications must be submitted through the links provided.

Background

The second target station (STS) is a >$1Billion, Department of Energy project to be constructed at the ORNL Spallation Neutron Source (SNS).

The STS will provide entirely new capabilities for the study of a broad range of materials with neutron scattering and support thousands of users from the physical, materials, and applied sciences and industry. The science capabilities provided by the instrument suite at the STS will complement those of the two existing DOE Office of Science neutron scattering user facilities at ORNL, the First Target Station (FTS) of the SNS, and the High Flux Isotope Reactor (HFIR).

The STS will deliver the highest peak brightness of cold neutrons in the world, which together with advances in neutron optics, instrumentation, and detectors, will ensure US leadership in neutron scattering for decades to come.

STS Diffraction Instrument Development Scientist

https://jobs.ornl.gov/job/Oak-Ridge-STS-Diffraction-Instrument-Development-Scientist-TN-37934/667295500/

STS Small Angle Neutron Scattering Instrument Development Scientist

https://jobs.ornl.gov/job/Oak-Ridge-STS-Small-Angle-Neutron-Scattering-Instrument-Development-Scientist-WA-37830/664911900/

STS Reflectometer Instrument Development Scientist

https://jobs.ornl.gov/job/Oak%2C-Ridge-STS-Reflectometer-Instrument-Development-Scientist-TN-37830/667300900/

STS Neutron Detector Scientist

https://jobs.ornl.gov/job/Oak-Ridge-STS-Neutron-Detector-Scientist-TN-37830/664914500/


[Post Date: August 12, 2020]


Protein Biochemist position at Sosei Heptares

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Description:

We are now seeking an experienced membrane protein biochemist to join the Protein Expression and Biochemistry group at our research facility on Granta Park, Cambridge, UK, working on membrane protein biochemical characterisation to enable drug discovery efforts.

At Sosei Heptares we are equipped with state-of-the-art protein expression, purification, SPR, mass-spec, crystallisation and cryoEM facilities. Applicants should be proficient in the expression and purification of challenging membrane proteins destined for biochemical, biophysical and structural studies. A proven track record of publications related to the expression, purification, and biochemical characterisation of difficult membrane protein targets in peer-reviewed journals is highly desirable.

This is an exceptional opportunity to participate in pioneering science with an Industry-leading Drug Discovery company.

The successful candidate is expected to:

  • Express and purify challenging membrane proteins
  • Perform appropriate quality control analyses and biochemically and biophysically characterise purified membrane proteins
  • Keep up to date, propose, develop, implement and optimise new techniques in the fields of membrane protein expression, purification and biochemical characterisation
  • Collaborate with other Sosei Heptares scientists on research projects, working closely with molecular biologists, biophysicists and structural biologists
  • Prepare and effectively present results (written and oral) to program teams

Have strong interpersonal skills and interact effectively with collaborators across a wide range of disciplines

Requirements

  • Candidates should have or are about to obtain a PhD in biochemistry, biophysics or a related discipline
  • Possess extensive molecular biology skills and be knowledgeable in expression construct design and engineering
  • Proficient in the expression of membrane proteins from baculovirus/insect cells and/or mammalian cells
  • Proficient in the purification and extensive biochemical characterisation of membrane proteins
  • Familiar with the biochemical and biophysical techniques used to characterise proteins such as luminescence, fluorescence and FRET-based techniques
  • Candidates should understand the requirements of purified membrane proteins destined for structural (X-ray and/or CryoEM) and biophysical studies (SPR, mass spec)

Other information

Applicants must be able to demonstrate proof of the right to work in the United Kingdom.

The successful candidate will be employed by Heptares Therapeutics Ltd, a UK wholly owned subsidiary of Sosei Group Corporation. 

We offer a competitive salary, commensurate with qualifications and experience, and benefits package including pension and healthcare schemes.

Applications should include a covering letter, providing a short description of the background to their interest in the role, with curriculum vitae including the names and contact details for two referees. Please apply through our on-line jobs portal with your application in pdf format, quoting reference number 2020-5BMS.

The closing date for applications is 4th September 2020

Strictly No Agencies


[Post Date: August 12, 2020]


Postdoctoral Fellow - Marquez/McCarthy Teams: Innovative approaches for automated crystallography and high throughput X-ray based ligand screening

View the Job Posting Here

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Description:

EMBL Grenoble is looking for a postdoctoral scientist to play a key role in the exploitation of the upgraded MASSIF-1 beam line at the ESRF with a focus on the development of innovative approaches to automated crystallography and ligand screening. EMBL and ESRF have pioneered fully automated diffraction data collection on MASSIF-1 and the EBS associated upgrade of the beamline will provide a more brilliant beam and new experimental capabilities. The Marquez Team has developed automated pipelines for crystallographic fragment screening based on the CrystalDirect technology and the CRIMS software that they apply to study targets of biotechnological and biomedical relevance. This Team also operates the High Throughput Crystallization Facility (HTX Lab) providing access to fully automated, remote controlled crystallography pipelines. The successful candidate will be jointly associated with the Marquez and McCarthy teams and will work with the EMBL instrumentation and the ESRF Structural Biology Group on projects related to MASSIF-1, including the integration of the CrystalDirect technology directly on the beamline.

Your role

We are looking for a highly motivated scientist with extensive experience in protein crystallography and a strong interest in methods development. You will cooperate with the MASSIF-1 beamline Scientist and the HTX lab Team towards the development and operation of the upgraded MASSIF-1 beamline with a focus on expanding its capabilities to support automated fragment screening and crystallography pipelines, exploiting the unique experimental opportunities provided by the integration of the CrystalDirect technology in a beamline environment. Specifically, you will:

• Develop new plate to beam techniques such as automated online soaking protocols and humidity control experiments.
• Develop new approaches for fragment screening that take advantage of the unique MASSIF-1 and EBS upgrade capabilities
• Develop and test new data collection workflows on the ESRF beamline MASSIF-1 [kappa/helical/room temperature etc]
• Beamline and HTX lab user support

Moreover, you will participate in research projects involving fragment screening and development of chemical tools on targets of biomedical relevance. Experience in the operation of synchrotron beamlines will be highly appreciated as well as experience in the analysis of small molecule protein interactions. You should be able to work both independently and collaboratively with other group members and external collaborators.

You have

A PhD in Structural Biology, Physics, Biochemistry or related disciplines. At least 3 years of experience in protein crystallography including experience in diffraction data collection at synchrotron sources. A willingness and motivation to engage in method development and beamline operation. Excellent communication skills and relational abilities.

You might also have

Experience in the operation of synchrotron beam lines, ligand screening or the analysis of small molecule-protein interactions through protein crystallography would be beneficial as well as some software development skills.

Why join us

This post offers a unique opportunity to contribute to the substantial upgrade and further development of highly automated data collection capabilities of ID30A-1/MASSIF-1 post ESRF-EBS upgrade and drive projects in translational biomedical research.

What else you need to know

Further information about this position can be obtained from Andrew McCarthy (andrewmc@embl.fr) or Josan Marquez (marquez@embl.fr).

See also http://www.embl.fr.

Please note interviews are planned for early November.
Location: Grenoble, France
Staff Category: Postdoctoral Fellow
Contract Duration: 3 years
Grading: Postdoctoral fellow
Closing Date: 12 October 2020
Reference Number: GR00148


[Post Date: August 12, 2020]


Postdoc UT Health Science Center, San Antonio, Texas

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Description:

The laboratory of Dr. Yogesh Gupta at University of Texas Health Science Center in San Antonio is seeking an enthusiastic Postdoctoral Fellow to study the structure and function of nucleoproteins in infectious diseases and cancer. We combine structural biology tools (X-ray, cryo-EM, NMR) with cell-based methods to address mechanistic questions and exploit this knowledge for drug development. Please visit below websites to learn about our research program –

https://www.nature.com/articles/s41467-020-17496-8

http://ccri.uthscsa.edu/YGupta.html

Preference will be given to applicants with demonstrated experience in macromolecular crystallography. Candidates are expected to possess strong organizational, interpersonal skills, and ability to work as part of a team. An ideal candidate should hold (or soon expect to hold) a Ph.D. or equivalent degree in biochemistry/biophysics/structural biology and have no more than 2 years of postdoc experience.

Salary is competitive. San Antonio offers affordable cost of living and there is no state income tax in Texas. If interested in applying, please send a short description of your research accomplishments, and CV with a list of 3 references to Dr. Yogesh Gupta (email: guptay@uthscsa.edu).

The Greehey Children’s Cancer Research Institute is a unique specialized cancer research center focusing on basic and translational research in childhood cancer and occupies a state-of-the-art 100,000 sq. foot research facility on the university’s Greehey Academic and Research Campus. San Antonio is the nation’s seventh largest city and is located at the edge of the beautiful Texas Hill Country. San Antonio offers a rich, multi-cultural community, affordable cost of living, excellent weather and a thriving biomedical industry. All Postdoctoral appointments are designated as security sensitive positions. The University of Texas Health Science Center at San Antonio is an Equal Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities.


[Post Date: August 3, 2020]


Postdoc University of Pittsburgh, Protein Design and Engineering for Drug Development

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Description:

Description: a postdoctoral position is available in the Shi laboratory of antibody biotechnology and proteomics at the Department of Cell Biology, University of Pittsburgh School of Medicine (UPMC). The laboratory is at the forefront of developing transformative new technologies that integrate proteomics, computational biology, and structural approaches for large-scale antibody (especially camelid VHH antibody/ nanobody) discovery and characterization.  The lab is also interested in applying these techniques to develop novel nanobody-based therapies for some of the most devastating diseases including COVID-19, cancer, and neurodegeneration. The lab is currently funded by several grants including the NIH, MJFF, and Alzheimer Foundation. More information about our research could be found here at www.shi-lab.org. For the successful incumbent, the initial appointment is 12 months with the possibility of renewal. Compensation will follow standard NIH Post-Doc salary rates and is based on experience. We strongly support the career development of our colleagues and trainees. A listing of Pitt employee benefits is available at https://www.hr.pitt.edu/current-employees/benefits

Highly motivated individuals with a background in biochemistry, bioengineering, biophysics or structural biology (especially membrane protein structural biology) are welcome to apply. Successful candidates should have excellent communication skills and the desire to lead research projects. Interested candidates may submit their CV including names and contact information for two-three references, a short description of their research experience, and research goals to Yi Shi at (yi.shi@pitt.edu). For more information about our research visit: https://www.shi-lab.org/

Pittsburgh: As the second-largest city in Pennsylvania, Pittsburgh is best known as "the city of Bridges". In 2015, Pittsburgh was listed among the "eleven most livable cities in the world" and has been considered as one of the most livable cities in the United States.

The University of Pittsburgh is an Equal Opportunity Employer.


[Post Date: August 3, 2020]


Sanofi Postdoctoral Fellowship: Computational Scientist for Antibody Engineering (Framingham, MA)

View the Job Posting Here

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Description:

The Protein Engineering group within Sanofi Large Molecule Research Department is seeking a highly talented Computational Scientist for a postdoctoral position. We use leading-edge structural biology and computational tools to support biologics project needs from Sanofi’s multi-targeting, multi-modality research pipeline. Our team has a great track record of patents and publications, including Science, Nature Cancer, and Nature Communications, in the area of biologics characterization, antibody engineering and multi-specific antibodies. This postdoc project will focus on developing a machine learning approach to predict epitope-paratope, given any antibody-antigen pair, by combining in-depth understanding of structure biology, antibody engineering, and large datasets both internally and externally. The successful candidate will be with Ph. D. degree in related area and has an advanced understanding and practical experience with developing and applying complex machine learning solutions for structural biology data. The successful candidate will gain deeper insight into drug development process and transform AI/ML algorithms into accelerating biologics discovery and development process.

Application Link: https://sanofi.wd3.myworkdayjobs.com/en-US/StudentPrograms/job/Framingham-MA/Sanofi-Postdoctoral-Fellowship--Computational-Scientist-for-Antibody-Engineering--Framingham--MA-_R2552646

About Sanofi:

Every day, Sanofi's 100,000 employees are committed to improve the lives of people around the world, with sustainable and responsible solutions and initiatives. Sanofi is recognized as one of the leading biopharmaceutical companies in the world and is pioneering innovation in biologics with the first approved nanobody drug, the first clinical stage tri-specific antibody, and a novel genetic codon expansion platform for new engineering capabilities. Details of the organization and the company’s mission and goals can be found on our website (http://www.sanofi.us/l/us/en/index.jsp).


[Post Date: August 3, 2020]


Computational Biology Scientist, Machine Learning in Large Molecule Research

View the Job Posting Here

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Description:

About the Company:

Every day, Sanofi's 100,000 employees are committed to improve the lives of people around the world, with sustainable and responsible solutions and initiatives. Sanofi is recognized as one of the leading biopharmaceutical companies in the world and is pioneering innovation in biologics with the first approved nanobody drug, the first clinical stage tri-specific antibody, and a novel genetic codon expansion platform for new engineering capabilities. Details of the organization and the company’s mission and goals can be found on our website (http://www.sanofi.us/l/us/en/index.jsp).

Overview:

Sanofi Large Molecule Research Platform is opening a new scientist/senior scientist role to seek a computational biologist with strong expertise in computational biology, bioinformatics, artificial intelligence (AI), machine learning (ML), and deep learning (DL).  The successful candidate will work in an interdisciplinary team to apply cutting-edge computation, AI/ML/DL, and structural biology technologies to resolve challenges in real-world drug discovery and make impacts to patients’ life. This is an exciting opportunity to contribute to the process of design and engineering revolutionary biologics, including multivalent, multi-targeting molecules by leveraging proprietary data coming from our industry-leading high-throughput automation platforms. The successful candidate will gain deeper insight into drug development process and transform AI/ML algorithms into accelerating biologics discovery and development process.

Your responsibilities include:

o   Evaluate and develop state-of-the-art computational methods to decode biophysical and geometrical features from antibody-antigen datasets and create predictive models for engineering.

o   Develop and apply complex machine/deep learning solutions to our high-content and high-quality proprietary datasets, as well as public datasets.

o   Perform data querying and feature extraction to improve current workflow for antibody/nanobody engineering, including affinity modification, cross-reactivity engineering, liability risk prediction and mitigation, multi-specific antibody engineering, and de novo antibody design.

o   Maintain a keen awareness of recent developments in data science, bioinformatics, and state-of-the-art of AI/ML/DL algorithms, aiming to accelerate development of new computational algorithms.

o   Effectively collaborate with colleagues with diverse scientific background, identify problems and opportunities, combine computational and structural analysis to support large molecule projects.

Basic qualifications:

o   MS with 5+ years’ or Ph. D. with 0-5 years’ experience in computational structural biology, bioinformatics, computational chemistry, or computational physics, with significant experience in data science and machine learning.

o   Understanding of protein structure and protein-protein interaction. Hands-on experience with structural analysis and optimization of biochemical and biophysical properties, like thermodynamics, with protein design tools e.g. Rosetta, BioLuminate, or MOE, etc.

o   Strong familiarity with core concepts in Deep Learning and Neural Networks including CNNs, RNNs, Embeddings, Transfer Learning, Attention-based Networks, Statistical Learning.

o   Familiarity with deep learning libraries such as Keras, TensorFlow, PyTorch, and bioinformatics pipelines

o   Experience of developing computational prediction models for protein engineering through programming with Python, Shell, or SVL, etc.  Experience with cloud computing, parallel computing, and/or supercomputing is expected.

o   Familiarity with protein structure or sequence featurization and learned embeddings. Experience with database mining, big data, and large-scale virtual screening using Bayesian optimization etc is desired.

o   Familiarity with Data Visualization tools/libraries and dimensionality reduction algorithms.

Preferred qualifications:

o   Understanding of biologics R&D process is a plus.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA

#LI-SA

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.


[Post Date: July 30, 2020]


Senior Associate – Protein Expression

View the Job Posting Here

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Description:

Category: Scientific
Job ID: R-102000
Location: Burnaby, BC, CA
Additional Location: Canada - Mississauga
Posted Date: 7/24/2020

Summary

Amgen is a global biotechnology company that discovers and develops breakthrough therapies to treat serious human illnesses. Our mission is to serve patients around the world and our medicines have made a dramatic difference in the lives of millions.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world’s leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen’s Therapeutic Discovery organization is seeking an enthusiastic, collaborative Senior Associate to join the Protein Technologies group at our Amgen British Columbia site. Protein Technologies is responsible for designing, planning and executing on the generation of key enabling reagents to support discovery of small and large molecule therapeutics and cutting-edge novel modalities.

Well-suited applicants will have a strong scientific background in recombinant protein expression in mammalian host systems, a deep scientific curiosity, and a positive approach to working in a team-based research environment. These individuals will also have a track record of creative problem-solving and enthusiasm for tackling difficult research challenges.

Responsibilities

  • Work within the Protein Technologies team to deliver high quality protein reagents to support the early pipeline
  • Grow and maintain cell lines for transient and stable transfections
  • Express a wide variety of protein classes, including soluble proteins, antibodies, and antibody fusions in mammalian cell hosts (HEK293, CHO) by transient and stable expression methods
  • Determine protein expression levels using SDS-PAGE, Western Blot, and Octet
  • Analyze and interpret scientific data, document experiments in lab notebooks and LIMS, and multi-task with focus on detail in a fast-paced environment
  • Leverage strong communication skills in planning and coordinating experiments and sample hand-offs with team members and partner functions

Basic Qualifications

Master’s Degree

OR

Bachelor’s degree and 2 years of scientific experience

Preferred Qualifications

  • Expertise in recombinant protein expression, including:

o   Mammalian tissue culture and aseptic technique

o   Recombinant protein expression in HEK293 and/or CHO

o   SDS-PAGE and Western blot analysis

o   Familiarity with Octet titer measurements

  • Demonstrated scientific analysis and problem-solving skills
  • Strong written and verbal communication and interpersonal skills
  • Desire to be a team player in a dynamic, cross-functional environment

Amgen endeavors to make its recruitment process accessible to any and all users. Reasonable accommodations will be provided, upon request, to applicants with disabilities in order to facilitate equal opportunity throughout the recruitment and selection process. Please contact TalentAcquisitionInquiries@amgen.com to make a request and ensure you include the requisition number.

Reasonable accommodations are available, upon request, to facilitate the equal participation of candidates with disabilities, should you be selected for an interview.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

http://careers.amgen.com/ShowJob/JobId/453495/


[Post Date: July 30, 2020]


Senior Scientist – Protein Technologies Team Lead

View the Job Posting Here

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Description:

Category: Scientific
Job ID: R-102328
Location: Burnaby, BC, CA

Title: Senior Scientist – Protein Technologies Team Lead

Reports to: Principal Scientist

Location: Burnaby

JOB SUMMARY

Amgen is a global biotechnology company that discovers and develops breakthrough therapies to treat serious human illnesses. Our mission is to serve patients around the world and our medicines have made a dramatic difference in the lives of millions.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world’s leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen’s Therapeutic Discovery organization is seeking an enthusiastic, collaborative Senior Scientist team lead to join the Protein Technologies group at our Amgen British Columbia site. Protein Technologies is responsible for designing, planning and executing on the generation of key enabling DNA and protein reagents to support discovery of small and large molecule therapeutics and cutting-edge novel modalities.

As a team lead within Protein Technologies, you will be responsible for managing a high-performing team with a mandate to produce high quality reagents to support the Amgen pipeline. You will be responsible for the operational, strategic, and scientific management of the group and will also actively participate in the science through hands-on lab work and implementation of enabling technologies and automation. You will also be responsible for aligning with our Protein Technologies group in South San Francisco and for initiating and driving collaborations with partner functions such as such as Antibody Discovery, Therapeutic Areas, and Molecular Structure.

Well-suited applicants will have a strong scientific background in recombinant protein expression, purification, and analytics, a deep scientific curiosity, and demonstrated success in project and personnel management.

Basic Qualifications

Doctorate degree and 3 years of Scientific experience
OR
Master’s degree and 6 years of Scientific experience
OR
Bachelor’s degree and 8 years of Scientific experience

Preferred Qualifications

  • Ph.D. in Biochemistry, Biophysics, Chemistry or Molecular Biology and postdoc from a leading institution or biotechnology company
  • 4+ years of industry experience
  • A track record of scientific accomplishments and project leadership in biologics drug development as evidenced by peer-reviewed publications, patents, or pipeline contributions
  • 2+ years of managing a high-performing team with a focus on protein expression, purification, and analytics
  • Expertise in recombinant protein expression in transient and stable mammalian hosts such as HEK293 and CHO
  • Expertise in purifying a range of different protein types (e.g. extracellular domains, glycoproteins, monoclonal and multi-specific antibodies, membrane proteins) using multiple chromatographic methods (e.g. affinity, ion exchange, size exclusion)
  • Expertise in protein analytics, including HPLC-SEC and LC-MS
  • Experience with increasing productivity through automation
  • Microbial protein expression experience
  • Familiarity with processes in antibody discovery
  • Strong written and verbal communication and interpersonal skills
  • Ability to inspire and grow a high-performing team, chart and set team goals into action, and forge productive cross-site collaborations with partner functions

Amgen endeavors to make its recruitment process accessible to any and all users. Reasonable accommodations will be provided, upon request, to applicants with disabilities in order to facilitate equal opportunity throughout the recruitment and selection process. Please contact TalentAcquisitionInquiries@amgen.com to make a request and ensure you include the requisition number.

Reasonable accommodations are available, upon request, to facilitate the equal participation of candidates with disabilities, should you be selected for an interview.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

http://careers.amgen.com/ShowJob/JobId/454113


[Post Date: July 30, 2020]


Postdoc Institute for Protein Innovation, Boston, USA

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Description:

The Bahl Lab at the Institute for Protein Innovation (IPI) in Boston is recruiting Postdoctoral Fellows. We use protein design to accelerate drug discovery and to engineer new lead therapeutic molecules. In addition to traditional academic collaborations, we work closely with pharmaceutical and biotech companies, as well as venture capital firms.

We are looking for translationally-minded scientists who want their work to have a direct impact on the world. We will provide training in computational protein design using Rosetta, including de novo protein design and the design of protein function and biophysical properties. Postdoctoral Fellows at IPI leverage our high-throughput automated laboratory infrastructure.

We are especially excited to expand our work in the following research areas:

  • prediction and design of protein developability for therapeutic applications
  • engineering of de novo miniprotein/peptide lead therapeutics for oncology, infectious disease, hypertension and diabetes, etc.
  • antibody design, including de novo paratope design
  • enzyme design

Strong candidates will have demonstrated expertise in one or more of the following:

  • protein biochemistry: protein production and biophysical characterization, enzymology
  • structural biology: cryo-EM, X-ray crystallography, NMR
  • immuno-oncology: cell culture models, fluorescence activated cell sorting
  • traditional protein engineering: directed evolution, library construction, yeast and/or phage display
  • computational biology: machine learning, data science, molecular dynamics and/or modeling

If you are excited to join a team of protein designers working to tackle audacious projects aimed directly at improving human health, please send your CV to: chris.bahl@proteininnovation.org

About IPI 

The Institute for Protein Innovation is a non-profit organization that is advancing protein science to accelerate research and improve human health. The Institute is located at Harvard Medical School. IPI uniquely combines the freedom of academic exploration with the high-throughput scaling of industry to take on transformative protein-based initiatives that no other laboratory or organization can or will pursue. IPI is deploying state-of-the-art technologies to build a repository of powerful protein tools and reagents and share them through licensing and collaboration. These will enable new biomedical and therapeutic discovery for researchers in academia and industry alike. This constellation of vanguard technology and expertise positions IPI to train the next generation of entrepreneurs and protein scientists to lead the discovery of new medicines. 


The IPI is an equal opportunity employer and prohibits discrimination based on ethnicity, religion, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, socioeconomic status, marital or veteran status, etc. Candidates from underrepresented backgrounds are especially encouraged to apply.


[Post Date: July 30, 2020]


Scientist/Senior Scientist - Protein Purification - Abingdon Evotec

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Description:

Required Knowledge, Skills and Abilities:

  • Extensive knowledge of protein purification, demonstrated through the delivery of innovative solutions for drug discovery programs
  • A working knowledge and practical experience with AKTA systems will be highly advantageous
  • The successful candidate will have experience working in multi-disciplinary teams
  • Experience collaborating with scientists in external organisations would be an advantage

Responsibilities may include:

  • Supporting a project team by conducting experiments with defined, agreed objectives and timelines
  • Contributing to the design, execution and interpretation of experiments in a project team to accomplish project goals
  • Adapting scientific knowledge to resolve problems encountered in achieving defined goals with assistance from line manager or other team members to meet internal and project deadlines
  • Preparing reports of findings, presenting data, and collaborating with other scientists at Evotec
  • Presenting own work at project technical meetings, and department technical meetings when required
  • Demonstrating full command of all techniques and tools required for assigned responsibilities within the given project
  • Ensuring safe working practices of themselves and any direct reports
  • Complying fully with the company safety policy (including COPs and SOPs) when performing experiments
  • Reading scientific literature relevant to the project
  • Adhering to Lab Notebook guidelines regarding accurate documentation of lab experiments

Desirable Knowledge, Skills and Abilities:

  • Self-motivated, enthusiastic, cooperative and reliable
  • Knowledge of basic laboratory techniques, and understanding of the science underlying the techniques and experiments
  • Experience of working in a lab environment
  • The ability to adapt to changing demands whilst operating under pressure to deadlines
  • The ability to work accurately and with attention to detail
  • Good interpersonal skills and the ability to work well with other scientific staff
  • The ability to work well independently, and as part of a team
  • Good organisational and time management skills
  • Good verbal communication skills
  • Ability to maintain excellent laboratory records
  • Computer proficiency

Education and Experience:

  • PhD, MSc, BSc degree or equivalent in Biochemistry or related area

Candidates must be eligible to work in the UK.


[Post Date: July 30, 2020]


Visiting Research Specialist Position at the University of Illinois to Study Ribosome Structure

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Description:

The Polikanov Laboratory at the University of Illinois at Chicago (IL, USA) is looking for a talented, skillful, and highly motivated researcher to fill the Visiting Research Specialist position to study the structure and function of the bacterial ribosome.

The research in the Polikanov Laboratory is focused on understanding the basic principles of protein synthesis in bacteria, the modes of action of ribosome-targeting antibiotics, and the mechanisms of drug resistance at a structural level. More information about Dr. Polikanov's research can be obtained from the most recent publications (https://www.ncbi.nlm.nih.gov/sites/myncbi/yury.polikanov.1/bibliography/50395623/public/?sort=date&direction=descending) or found on the laboratory web-page (https://bios.uic.edu/bios/people/faculty/yury-polikanov). The successful candidate will be involved in the determination of high-resolution structures of ribosome functional complexes with various protein translation factors, tRNAs, and antibiotics using macromolecular X-ray crystallography and potentially cryo-EM techniques.

Basic qualifications:

  • BS degree in chemistry, biochemistry, biophysics, or a related field;
  • MS degree or higher is preferred;
  • Minimum 3 years of laboratory research experience;
  • Strong background in biochemistry and molecular biology;
  • Practical skills with the most standard methods currently used in molecular biology, and biochemistry (such as protein expression, purification);
  • Experience in structural biology (cryo-EM or X-ray crystallography) is desired;
  • Experience in RNA biology is desired.

The successful candidate is also expected to:

  • Act independently in terms of planning and executing the experiments;
  • Compile, analyze, and prepare data for publications;
  • Assist with training of graduate and undergraduate students.

For fullest consideration, please submit an application and cover letter describing your scientific interests and how your previous research accomplishments and scientific interests fit with the scope of the research in the Polikanov research group at https://jobs.uic.edu/job-board/job-details?jobID=133847 by August 14, 2020.

The University of Illinois at Chicago is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply. The University of Illinois may conduct background checks on all job candidates upon acceptance of a contingent offer. Background checks will be performed in compliance with the Fair Credit Reporting Act.

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[Post Date: July 28, 2020]


Postdoctoral position at Brown University

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Description:

The Deaconescu Lab at Brown University has one opening for a postdoctoral researcher. The laboratory's interests lie primarily in stress responses, with particular emphasis on responses to DNA damage and the mechanochemistry of DNA-based motors. We utilize a combination of biochemical, biophysical and structural techniques. (e.g. X-ray crystallography, small-angle X-ray scattering, transmission electron microscopy). Examples of work are: Brugger et al, Nature Communications (2020), Dorich et al, Genes & Development (2019), Vemu et al. Science (2018), Le TT et al. Cell (2018), Deaconescu et al. Photochemistry and Photobiology (2017), Kutter et al. JMB (2016), Szyk et al, Cell (2014), Deaconescu et al., PNAS (2012), Szyk et al., NSMB (2012) and Deaconescu et al., Cell (2006).

 A successful candidate should have an established track-record of publications in peer-reviewed journals; solid experience with protein biochemistry (including their purification from E.coli/yeast,  functional characterization and assay development).  Prior knowledge of crystallography and/or single-particle electron microscopy is highly desirable. Must be highly motivated and work independently as well as in a team. Excellent spoken and written English are required. New Ph.D. graduates are encouraged to apply. 

Interested candidates should send a CV, a one page research experience summary and contact information for three references to alexandra_deaconescu[at]brown.edu. Please use “postdoctoral candidate” as a subject.

Salary and starting date are negotiable.   Please write Postdoctoral Candidate in the e-mail subject header.   Brown University, an Ivy League school, is located in Providence, Rhode Island less than one hour away by train from Boston.   Rhode Island provides plenty of opportunities for outdoor recreation with beautiful beaches and sailing.

Lab webpage: https://deaconesculab.com    


[Post Date: July 27, 2020]


SGC Toronto - Postdoctoral Position in Structural Biology

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Description:

POSITION TITLE: Postdoctoral Position – Limited Term

DEPARTMENT: Structural Genomics Consortium (SGC), Faculty of Medicine

SUPERVISOR: Dr. Cheryl Arrowsmith

OVERVIEW:

The Structural Genomics Consortium (SGC) in the Faculty of Medicine, University of Toronto invites applications for the Postdoctoral position (Limited Term) to join the SGC’s structural biology team to investigate the structure, mechanism and druggability of human WD-repeat (WDR) domain containing proteins using X-ray crystallography, biochemistry and biophysics. WDRs are protein-protein interaction hubs that are often found in key regulatory complexes involved in ribosomal biogenesis, epigenetic regulation, cell cycle control and DNA repair (see Schapira et al., 2017, https://doi.org/10.1038/nrd.2017.179), (Grebien et al, 2015, https://doi.org/10.1038/nchembio.1859) and (Getlik et al., 2016, DOI: 10.1021/acs.jmedchem.5b01630). Many WDR proteins are associated with diverse diseases, especially cancer, yet the majority of them are understudied. We have demonstrated the druggability of WDR proteins and seek to develop chemical biology tools to elucidate the function and therapeutic potential of select members of this family. This multidisciplinary project is in collaboration with several AI-based drug-discovery companies, academic labs as well as pharmaceutical companies. The successful candidate will have a broad knowledge of protein biochemistry and X-ray crystallography, a passion for scientific research as applied to drug discovery, and be eager to work as a team player in a fast-paced multidisciplinary environment.

QUALIFICATIONS:

  • Ph.D. in biochemistry, molecular biology, structural biology, or related field, with at least one first authored publication in an internationally recognised peer-reviewed journal.
  • Strong experience with recombinant protein expression, and purification, is required.
  • Experience in X-ray crystallography and/or cryo-EM is highly desirable.
  • Experience with in vitro biophysical methods for protein-protein and protein-ligand interaction studies (e.g. DSF, SPR, FP, FRET, ITC, etc…) is valuable.
  • Strong communication skills, particularly the visual presentation of structural data.
  • Ability to work in a team, communicate, and give/receive constructive feedback and high attention to detail, excellent organizational and documentation skills.
  • Experience in preparing manuscripts for submission to peer review publications/journals and presenting findings at meetings and conferences.

To Apply:

Please forward your CV and contact information for 2-3 references to l.halabelian@utoronto.ca with the subject line “WDR Postdoc”. Position will remain open until filled.

The SGC is a not for profit, public-private partnership working with academia and ten pharmaceutical companies to carry out open access research relevant to human health and drug discovery.
www.thesgc.org

The University of Toronto and its affiliated hospital research institutes comprise one of the largest and most productive centers of biomedical research in North America. Located in vibrant downtown Toronto, the University provides an outstanding opportunity for scientific research, and career development.

The University of Toronto is strongly committed to diversity within its community and especially welcomes applications from racialized persons / persons of colour, women, Indigenous / Aboriginal People of North America, persons with disabilities, LGBTQ persons, and others who may contribute to the further diversification of ideas.
All qualified incumbents are encouraged to apply; however, Canadians and permanent residents will be given priority.

Closing Date: 
Thursday 1st October 2020


[Post Date: July 23, 2020]