Postdoctoral Research Assistant Queen Mary University of London - School of Biological & Behavioural Sciences

View the Job Posting Here

Description:

[Post Date: May 26, 2023]

Research Fellow in Integrative Structural Biology - Institute of Cancer & Genomic Sciences

Description:

Position Details

Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences

Location: University of Birmingham, Edgbaston, Birmingham UK

Full time starting salary is normally in the range £33,348 to £43,155 with potential progression once in post to £45,737  

Grade 7

Full Time, Fixed Term Contract for 3 years

Closing date: 30 June 2023

Background

The research group studies the functional mechanisms of proteins, nucleic acids and their complexes by integrative structural biology. The laboratory uses and develops high-field NMR spectroscopy methods as major structural biology tool, in combination with several other techniques. The Research Fellow will work in one of the following fields: RNA metabolism, regulation of gene expression, DNA repair, signalling. The post holder will use NMR spectroscopy, X-ray crystallography and/or Electron Microscopy, as well as Mass Spectrometry and Small Angle Scattering, to study the structure of protein–protein or protein–nucleic acids complexes and discover the mechanisms of their function and regulation. There are opportunities to develop new approaches to integrative structural biology with the combination of the techniques mentioned above. In addition, the Research Fellow will use molecular biology, biophysical and biochemical techniques to characterize biomolecular complexes and their activity in vitro and cellular biology approaches to verify the functional mechanisms in vivo.

We are a group of highly motivated structural biologists with an interdisciplinary, international background. We offer a first-class research environment with state-of-the-art equipment in molecular biology and biochemistry and the best equipped biomolecular NMR facility in the UK (comprising 1000, 900 and 800 MHz spectrometers equipped with cryoprobes and MAS probes for both solution- and solid-state NMR spectroscopy). Excellent EM instrumentation is available at the Midlands Regional Cryo Electron Microscope Facility in Leicester.

Summary of Role

• Work within specified research grants and projects and contribute to writing bids
• Operate within area of specialism
• Design and perform experiments
• Analyse and interpret research findings and results 
• Contribute to generating funding 
• Contribute to licensing or spin out deals with demonstrated commercial success (such as revenues, asset or company sales, IP generated) and/or public understanding of the discipline or similar

Main Duties / Responsibilities

The responsibilities may include some but not all of the responsibilities outlined below.

• Develop research objectives and proposals for own or joint research, in the area of interest of the hosting laboratory (Prof. T. Carlomagno)
• Contribute to writing bids for research funding
• Acquire, analyse and interpret data - structural biology, biochemical and biophysical data.
• Apply knowledge in a way which develops new intellectual understanding
• Disseminate research findings for publication, research seminars etc
• Supervise students on research related work and provide guidance to PhD students where appropriate to the discipline
• Contribute to developing new models, techniques and methods 
• Undertake management/administration arising from research
• Contribute to Departmental/Institute research-related activities and research-related administration
• Contribute to enterprise, business development and/or public engagement activities of manifest benefit to the College and the University, often under supervision of a project leader
• Collect research data; this may be through a variety of research methods, such as scientific experimentation and literature reviews
• Present research outputs, including drafting academic publications or parts thereof, for example at seminars and as posters 
• Deal with problems that may affect the achievement of research objectives and deadlines
• Promotes equality and values diversity acting as a role model and fostering an inclusive working culture.

Person Specification

• PhD (or near to completion) in Biophysics/ Biochemistry/ Chemical Biology/ Structural Biology or related areas. Or, equivalent qualifications.
• Proficiency in either biomolecular NMR spectroscopy or single-particle electron microscopy, both in data acquisition and analysis.
• Practical experience in a biochemical laboratory and/or handling nucleic acids.
• High level analytical capability
• Ability to communicate complex information clearly
• Fluency in relevant models, techniques or methods and ability to contribute to developing new ones
• Ability to assess resource requirements and use resources effectively 
• Contribute to the planning and organising of the research programme and/or specific research project
• Co-ordinate own work with others to avoid conflict or duplication of effort
• Knowledge of the protected characteristics of the Equality Act 2010, and how to actively ensure in day to day activity in own area that those with protected characteristics are treated equally and fairly
• Willingness to work in a competitive, international environment.

Further particulars can be found here.

Informal enquires to Professor Teresa Carlomagno., email: T.Carlomagno@bham.ac.uk

Valuing excellence, sustaining investment

We value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community and are open to discussions around all forms of flexible working.

[Post Date: May 26, 2023]

Research Associate - Life and Physical Sciences

View the Job Posting Here

Description:

[Post Date: May 26, 2023]

Post-doctoral post at ICR with CR-UK Catalyst Grant

View the Job Posting Here

Description:

Post-doctoral post at ICR to develop LMO2 PROTAC compounds for leukaemia treatment

Our Chromosomal Translocation and Intracellular Antibody Therapeutics Group is within the Division of Cancer Therapeutics and is focused on new strategies using intracellular antibodies, and derivates, for therapy aimed at hard-to-drug chromosomal translocation gene products. This work includes intracellular antibodies for inhibiting transcription factors and protein-protein interactions.

The approach so far has resulted in compounds that bind to the chromosomal translocation LMO2 transcription factor and that effect T cell leukaemia cell growth. The aim is to develop these compounds into drugs for refractory T-cell acute leukaemias. All the scientific expertise is in place to make this possible and our approach is multi-disciplinary, integrating molecular biology, cell biology, antibody design, structural biology, and chemical biology. The post is part of a CR-UK funded Therapeutic Catalyst Award in collaboration with Professor Angela Russell (University of Oxford, Dept of Chemistry). We aim to develop our LMO2 binding compounds to pre-clinical efficacy using structure-based drug evolution. These will be the first compounds to be derived from an intracellular antibody binding site that have progressed towards phase I clinical trials. The post should lead to further work in the group to drug using our intracellular antibody approach.

If you are interested in developing antibody derived compounds using recombinant protein expression and structural biology for cancer drug development, apply for the postdoctoral position (ID624) available in Professor Terry Rabbitts’ group within the Division. You should have a PhD in a biological subject and have experience in working with recombinant proteins, in particular antibodies and transcription factors. You should have experience with protein engineering and as well as in methods such as X-ray crystallography. Experience with cell-based models will be needed for evaluation of compounds binding to LMO2.

The post holder will be responsible for protein production and purification, protein crystallisation, structure determination by X-ray crystallography and subsequent cell-based analysis of compounds. We benefit from excellent access to Diamond Light Source synchrotron at the Harwell Science and Innovation campus, Didcot, UK, for X-ray data collection. 

The Institute of Cancer Research (ICR), London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Today, the ICR leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment. Together with our hospital partner The Royal Marsden, we are rated in the top four centres for cancer research and treatment worldwide. As well as being a world-class institute, we are a college of the University of London. The ICR is committed to our mission to make the discoveries that defeat cancer.

ICR is split between labs in Chelsea and Sutton and the Division of Cancer Therapeutics is located in the new Centre for Cancer Drug Discovery building at the Sutton site. It is dedicated to the discovery and development of novel therapeutics for the treatment of cancer.

The starting salary will be in the range £40,107 to £42,402 p.a. inclusive (based on previous postdoctoral experience). The post is offered on a fixed term contract of up to 1.5 years. Informal enquiries to terry.rabbitts@icr.ac.uk

Please DO NOT send your application to Professor Rabbitts but apply via the e-recruitment system on our website www.icr.ac.uk.

For more details see the following link:

https://jobs.icr.ac.uk/vacancies/624/postdoctoral-training-fellow-cr-uk-therapeutic-catalyst-grant-prof-t-rabbitts--id624.html

Closing date:  13^th June 2023

[Post Date: May 24, 2023]

Post-Doc in DNA Crystallography

Description:

Univ. of Munich

Begins Fall 2023

The post-doc will have a key role in several projects focused on crystallization and crystallographic structure elucidation of DNA and DNA-mimic foldamers (illustrations below are crystal structures). The group has frequent access to ESRF and DESY and a brand new home source.

Desired profile:- Background: PhD in nucleic acid crystallography
- Extensive experience in crystal growth of nucleic acids using hanging/sitting drop methods, crystal handling, data collection and crystallographic structure elucidation
- Additional experience in some of the following: measuring on an X-ray home source, nucleic acid-based nanotechnology, biophysics, molecular modelling.
- Creativity, autonomy, team spirit, leadership skills
- Wish to work in a multidisciplinary environment at the chemistry-biology interface.

Applications: Send a CV and ask reference letters to be sent by e-mail to Prof. Ivan Huc (ivan.huc@cup.lmu.de)

Group website: https://huc.cup.uni-muenchen.de/

References: Angew. Chem. Int. Ed. 2014, 53, 14424; Nucleic Acids Res. 2016, 44, 1936; ChemBioChem 2016, 17, 1911; Angew. Chem. Int. Ed. 2020, 59, 1606; Nat. Chem. 2018, 10, 511; Nucleic Acids Res. 2019, 47, 5511

[Post Date: May 17, 2023]

Two PDRA positions (36 months from October 23) at the University of Liverpool

Description:

We have a Chemistry PDRA and a Biophysics-structural biology PDRA positions to develop non-covalent binders to SOD1 suitable as PROTAC degraders for the treatment of motor neuron disease association. The Chemistry PDRA position would be based in Chemistry department (Professor O’Neill/Dr Nixon), The second PDRA would be based in the Biosciences complex (Professor Samar Hasnain/Dr Antonyuk/Dr. Awais). The project will benefit from collaboration with leading PROTAC expert at Dundee (Ciulli) and team at the Alzheimer's Research UK UCL Drug Discovery Institute (ARUK UCL DDI) led by Fiona Ducotterd. We aim to provide novel scaffolds that bind to the as-yet unexploited validated pocket surrounding Trp32. We will investigate for the first time, a fragment-based approach to drug design targeted against destabilised SOD-1. Direct crystallographic visualisation will be used to undertake lead optimisation and designing of CNS penetrant versions of initial small molecules hits. This non-covalent binding is suitable for a PROTAC approach. In-cell visualisation of aggregation and cell death would be undertaken using confocal microscopy. Applicants with relevant experience are encouraged to make informal enquiries via email to s.s.hasnain@liverpool.ac.uk, pmoneill@liverpool.ac.uk and S.Antonyuk@liverpool.ac.uk

[Post Date: May 15, 2023]

Postdoctoral Position at the Department of Biochemistry and Redox Biology Center

View the Job Posting Here

Description:

University of Nebraska-Lincoln, Lincoln NE, USA

We are looking for a highly motivated postdoc to work on the structural and mechanistic understanding of iron-sulfur proteins involved in redox sensing, stress response and antibiotic resistance in Dr. Limei Zhang’s group at the Department of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln. The position will offer a competitive salary and benefits.

Zhang Group: With funding support from both NIH and NSF, the Zhang Group combines state-of-the-art structural biology approaches including cryo-EM, and X-ray crystallography with biochemical, biophysical, and molecular biological methods to investigate novel metalloproteins involved in redox reactions and infectious diseases. For more information about the Zhang Group, please visit the website: https://biochem.unl.edu/limei-zhang.

Job responsibilities: The postdoctoral fellow is expected to independently design and conduct high-quality research experiments for the assigned project under the supervisor’s guidance; analyze data and draft manuscripts for publication; take roles in the lab maintenance with other group members; and assist the supervisor to mentor undergraduate and graduate students.

Qualifications: The required qualifications include a recent Ph.D. degree (or expected soon) in biochemistry, biophysics, chemistry, microbiology or a related field; a strong record in conducting high-quality research in structural biology or molecular biology. Experience in transcriptional regulation, biomolecular interaction, or structural biology (X-ray crystallography or cryo-EM) is highly desirable.

Training: The postdoc fellow will have the opportunity to learn comprehensive methods in preparation and characterization of metalloproteins in the Zhang group and first-hand training in cryo-EM in the collaborating research center supported by the NSF EPSCoR Research Fellowship.

Environment: The University of Nebraska-Lincoln is located in a vibrant and safe city offering an outstanding and affordable quality of life, and numerous multi-cultural and entertainment benefits. The Redox Biology Center is organized as a broad-based interdisciplinary and multi-institutional entity involving researchers from the University of Nebraska-Lincoln and the University of Nebraska Medical Center in Omaha and offers a supportive and collaborative international environment as well as access to cutting-edge proteomics, metabolomics, crystallography, and NMR facilities. We are also expected to have a cryo-EM instrument (Glacios w/Falcon 4i, Selectris EF & Ceta-D camera) installed at UNL in 2023.

Recognizing that diversity within a context of inclusivity enhances creativity, innovation, impact, and a sense of belonging, the Institute of Agriculture and Natural Resources (IANR) and the Department of Biochemistry are committed to creating learning, research, Extension programming, and work environments that are inclusive of all forms of human diversity. We actively encourage applications from and nominations of individuals from underrepresented groups.

How to Apply: To apply for the position, please submit a letter of interest with a short summary of past research experience; your curriculum vitae, and contact information for three professional references, including phone numbers and emails to limei.zhang@unl.edu

As an EO/AA employer, qualified applicants are considered for employment without regard to race, color, ethnicity, national origin, sex, pregnancy, sexual orientation, gender identity, religion, disability, age, genetic information, veteran status, marital status, and/or political affiliation. See http://www.unl.edu/equity/notice-nondiscrimination. 

[Post Date: May 10, 2023]

Postdoc IBS (Institut de Biologie Structurale) in Grenoble

Description:

A 2.5-year postdoctoral research position financed by the French National Research Agency (ANR) is available at the Bacterial Pathogenesis Group (A. Dessen) at the IBS (Institut de Biologie Structurale) in Grenoble. Our group uses structural biology tools to understand mechanisms employed by bacteria to initiate infections and to synthesize their cell wall. Candidates should have experience in molecular biology, soluble and membrane protein biochemistry and X-ray crystallography. This structural biology project will take advantage of the expertise in the lab working with virulence factors and their complexes in an environment with dedicated X-ray crystallography and electron microscopy facilities.

Deadline June 9th

CVs (including publication list and reference names) and queries should be sent to: andrea.dessen@ibs.fr

[Post Date: May 9, 2023]

Postdoctoral Position at the Ohio State University

Description:

Applications are invited for a joint postdoctoral scientist position in the laboratories of Dr. Sarah Heissler and Dr. Krishna Chinthalapudi at the Ohio State University. The research project focuses on understanding the role of myosin motors and cytoskeletal proteins in health and disease. We combine state-of-the-art structural biology approaches including cryo-EM, and X-ray crystallography with biochemical, biophysical, and cell biological methods to investigate the structure and function of myosin motors and their regulation by cytoskeletal proteins.

Our laboratories are equipped with state-of-the-art instrumentation for the proposed studies and have generous access to a Titan Krios G3i Cryo-TEM equipped with a bioquantum imaging filter and a K3 direct electron detector, imaging phase plates, and an image spherical aberration corrector. In addition, our labs have access to a Glacios with a Falcon III detector and a Ceta-D camera for MicroED analysis at the world-class Center for Electron Microscopy and Analysis (CEMAS) at the Ohio State University.

Candidates must have a Ph.D. degree and strong practical experience in structural biology. Experience in molecular biology techniques, structural biology, and/or high-resolution imaging are desirable.

To be considered for this position, please email your curriculum vitae, a short cover letter with research experience and interests, and contact information for three references to Sarah Heissler (sarah.heissler@osumc.edu) and Krishna Chinthalapudi (krishna.chinthalapudi@osumc.edu).

[Post Date: May 4, 2023]

Research Coordinator

View the Job Posting Here

Description:

Job Location

Oklahoma-Norman-Norman Campus

Schedule

Full-time

Work Schedule: 8 AM - 5 PM Monday - Friday

Salary Range: Targeted salary $45,000 based on experience

Benefits Provided: Yes 

Required Attachments: Resume, Cover Letter 

--- 

The Chemistry department is looking for a Research Coordinator who will provide assistance to research staff for Dr. Peters by conducting simple research experiments, collecting data and samples, keeping records, conducting literature searches, analyzing data, and preparing reports

--- 

Required Education:  Bachelors degree, AND: 

• 24 months research or laboratory experience.

Equivalency Substitution: Will accept 48 months experience in lieu of the bachelors degree for a total of 72 months of experience

Skills:

• Proficient navigating and maintaining databases.
• Ability to speak, read and write clear, concise English.
• Strong oral and written communication skills.
• Proficient in Microsoft Office.
• Highly organized and able to handle multiple projects and deadlines.
• Able to produce reports and complete work within deadlines.
• Must be able to read and interpret policy as well as State and Federal regulations

Certifications:

• None

Advertised Physical Requirements:

• Ability to engage in repetitive motions. Must be able to crouch, crawl, and reach.
• Research or laboratory environment or in the field.

Departmental Preferences:

• None

Supervision:

• None

Special Instructions: If you are selected as a final candidate for this position, you will be subject to The University of Oklahoma Norman Campus Tuberculosis Testing policy.  To view the policy, visit https://hr.ou.edu/Policies-Handbooks/TB-Testing.

Diversity Statement: The University of Oklahoma is committed to achieving a diverse, equitable, and inclusive university community by recognizing each person's unique contributions, background, and perspectives. The University of Oklahoma strives to cultivate a sense of belonging and emotional support for all, recognizing that fostering an inclusive environment for all is vital in the pursuit of academic and inclusive excellence in all aspects of our institutional mission.

Equal Employment Opportunity Statement: The University of Oklahoma, in compliance with all applicable federal and state laws and regulations, does not discriminate based on race, color, national origin, sex, sexual orientation, genetic information, gender identity, gender expression, age, religion, disability, political beliefs, or status as a veteran in any of its policies, practices, or procedures. This includes, but is not limited to, admissions, employment, financial aid, housing, services in educational programs or activities, and health care services that the University operates or provides

Hiring contingent upon a Background Check?- Yes

Special Indications: None

[Post Date: May 4, 2023]

PostDoctoral Associate in Cheminformatics, Structural Chemistry

View the Job Posting Here

Description:

[Post Date: April 26, 2023]

Scientist in Protein Serial Crystallography

View the Job Posting Here

Description:

Job description

Applicant Profile

[Post Date: April 26, 2023]

Multiple Positions Deaconescu Laboratory Brown University

Description:

1. Lab Manager.

    Apply here.

    Or inquire with Alexandra directly by email.

1. Staff Scientist (with a primary focus on electron microscopy and a secondary focus on structure determination by X-ray crystallography)

    E-mail Alexandra (alexandra_deaconescu[at]brown.edu  with CV, letter of interest and contact information for 3 references.

   Or inquire with Alexandra directly by e-mail.

1. Research Technician. 

    Apply here.

   Or inquire with Alexandra directly by e-mail.

1. Postdoctoral Researcher. 

    E-mail Alexandra (alexandra_deaconescu[at]brown.edu  with CV, letter of interest and contact information for 3 references.

More information about the lab below.

The  Deaconesculaboratory's interests lie primarily in stress responses, with particular emphasis on responses to DNA damage. We utilize a combination of biochemical,

biophysical and structural techniques. (e.g. X-ray crystallography, electron microscopy). Examples of recent work are: Schwartz et al, Protein Science (2021), Brugger et al, Nature Communications (2020), Dorich et al, Genes & Development (2019), Vemu et al Science (2018), Le TT et al. Cell (2018), Szyk et al, Cell (2014). Positions are funded by two new multi-year grants from the NIH.

A successful postdoctoral or staff scientist candidate should have an established track-record of publications in peer-reviewed journals; solid experience with  protein biochemistry (their purification and assay development). We have a variety of projects available at different stages of development, including some that involve drug design. Prior knowledge of crystallography and/or single-particle electron microscopy is highly desirable. Knowledge of bacterial genetics also an asset. Must be highly motivated and work well independently as well as in a team. Excellent spoken and written English are required. 

Salary and starting date are negotiable. Brown University, an Ivy League school ranked as 5th best in the US by the Wall Street Journal, is located in Providence, Rhode Island less than one hour away by train from Boston. Rhode Island provides plenty of opportunities for outdoor recreation with beautiful beaches and sailing and we offer a friendly and supportive lab environment.

[Post Date: April 26, 2023]

Post-doctoral Position in Structural Biology/Biophysics at the University of Québec INRS

Description:

The laboratory of Professor Steven LaPlante at the INRS – Centre Armand-Frappier Santé Biotechnologie and NMX Research and Solutions Inc. are pleased to announce the opening of a joint post-doctoral position in biophysics in Laval, Québec, Canada.

Our joint research project is centered around discovering leads for future drugs. Using a combination of disciplines in biophysics, biochemistry and chemistry, we are exploring novel fragment-based lead discovery (FBLD) strategies to target a wide variety of diseases. Please visit the Laplante Lab website (https://www.laplante-lab.com/) for more information.

Candidates for this postdoc position will have completed a PhD degree with experience in biophysics techniques (either NMR, SPR, and/or X-ray crystallography). Experience with protein production will be a plus. He or she must be highly motivated and willing to work in a collaborative and multidisciplinary environment that bridges academia with the pharmaceutical industry.
Applicants should submit a cover letter and CV to Professor LaPlante (steven.laplante@inrs.ca). Review of applications will begin immediately and continue until the position is filled. The successful candidate will be expected to begin as soon as possible.

[Post Date: April 24, 2023]

Postdoctoral Associate – Transporter Structure and Function

Description:

The Paz lab at the Hauptman-Woodward Medical Research Institute (HWI) is seeking a highly motivated and talented postdoctoral researcher, to study the function and structure of transport proteins. The position is fully funded by the NIH and available immediately. Although this position is fully funded, the successful candidate will be strongly encouraged to apply for independent funding.

The successful candidate will contribute to a project aimed at elucidating the structural basis of medically relevant transporter function using cryo-electron microscopy (cryo-EM) and/or X-ray crystallography and various biochemical, biophysical, and functional tools. The candidate will also be responsible for interpreting and modeling the functional results and structures.

We offer a stimulating and collaborative research environment with access to state-of-the-art facilities that enable extensive structure/function studies. The candidate is expected to work independently, keep meticulous records, and will have the opportunity to present their research at national and international conferences and to interact with scientists from a variety of disciplines.

Requirements:

• A Ph.D. in structural biology, biochemistry, biophysics, or a related field.
• Extensive experience in molecular biology, protein production, purification, and biochemistry.
• Experience in protein structure determination.
• A proven record of scientific productivity, demonstrated by high-quality publications in peer-reviewed journals.
• Excellent communication and teamwork skills.

HWI is a prominent independent center for structural biology research, with outstanding facilities such as the National High-Throughput Crystallization Center, a cryo-EM Center, and managing the IMCA-CAT beamline 17-ID at the Advanced Photon Source at Argonne National Laboratory in Lemont, IL.

The postdoctoral associate position is based in Buffalo, NY. Application review will begin immediately, and the position will remain open until filled. The compensation level for this full-time position will be competitive and commensurate with the candidate’s qualifications. Furthermore, HWI provides a generous benefits package and Buffalo is one of the most affordable cities in the US.

To apply, please send a cover letter, a CV, and contact information for three references to apaz@hwi.buffalo.edu.

HWI is an equal-opportunity employer and is committed to creating a diverse and inclusive environment for all employees.

[Post Date: April 20, 2023]

NIH-funded Postdoctoral Associate position in Structural Virology at the University of Texas Health Science Center, San Antonio

View the Job Posting Here

Description:

The laboratory of Dr. Yogesh Gupta (http://ccri.uthscsa.edu/YGupta.html) is seeking an enthusiastic Postdoctoral Associate to study the structures and specificity of RNA modification enzymes. We will mainly use X-ray crystallography and cryo-EM to study the mechanisms and develop small molecule antiviral candidates. We provide a rich multi-disciplinary environment and access to cutting-edge technologies to our trainees.

Further details of our recent work can be found here:

Elife. 2022 Jan 21;11:e67150. doi: 10.7554/eLife.67150.

Nature Communications. 2021 Jun 2; 12: 3287. PMID: 34078893. doi: 10.1038/s41467-021-23594-y

Nature Communications. 2020 Jul 24;11(1):3718. PMID: 32709886. doi: 10.1038/s41467-020-17496-8

Preference will be given to applicants with demonstrated experience in protein purification from insect or mammalian cells, protein/nucleic acid biochemistry, X-ray crystallography, and cryo-EM. Candidates are expected to possess strong organizational and interpersonal skills and the ability to work independently but also effectively and collaboratively as part of a team. An ideal candidate should hold (or soon expect to) a Ph.D. or equivalent degree in biochemistry/biophysics/structural biology.

The Greehey Children’s Cancer Research Institute (GCCRI) is a unique, specialized cancer research center of UT Health Science Center San Antonio, focusing on basic and translational research. It occupies a state-of-the-art 100,000 sq. foot research facility on the university’s Greehey Academic and Research Campus. The GCCRI has significant external funding, a large endowment from the state, and links to philanthropic entities. San Antonio is the nation’s seventh-largest city and is located at the edge of the beautiful Texas Hill Country. San Antonio offers a rich, multicultural community, affordable cost of living, excellent weather, and a thriving biomedical industry. There is no state income tax in Texas. Salary is competitive and commensurate with experience. 

Interested candidates can apply by sending a short description of their research accomplishments and a CV with the contact information of 3 references to Dr. Yogesh Gupta (email: guptay@uthscsa.edu).

All Postdoctoral appointments are designated as security-sensitive positions. UT Health San Antonio is an Equal Opportunity/Affirmative Action Employer, including protected veterans and persons with disabilities.

[Post Date: April 14, 2023]

Université Paris-Saclay - Postdoctoral researcher position

Description:

We are seeking for a highly motivated post-doctoral researcher to join the ChemSyBio lab at the Micalis institute (Université Paris-Saclay), located in Jouy-en-Josas near Paris. The position is funded for up to two years.

The research project is focused on the mechanistic and structural investigation of novel metalloenzymes and will combine several structural biology approaches (X-ray crystallography, SAXS, Cryo-EM). The candidate should have a a PhD in biochemistry, structural biology or related field. Experience in protein structure determination and protein expression/purification is a plus.

Our institute provides a vibrant and international environment for researchers interested in interdisciplinary research with access to state-of the art synchrotron radiation facilities.

Selected publications from our lab:
- Fyfe et al., 2022 Nature, 602(7896):336-342.
- Parent et al., 2018 J Am Chem Soc. ; 140(7):2469-2477
- Benjdia et al., 2017 Nature Chemistry ; 9(7):698-707
- Parent et al., 2016 J Am Chem Soc.; 138(48):15515-15518
- Benjdia et al. 2015 Nat Commun. 12;6:8377

Applications (including CV and reference letters) should be sent to Dr Olivier Berteau (olivier.berteau@inrae.fr) and Dr Alhosna Benjdia (alhosna.benjdia@inrae.fr).

[Post Date: April 14, 2023]

Postdoc Structural Determination of Dengue Viral RNA and Circular mRNA Based Ttherapeutics

Description:

We are seeking two enthusiastic and self-motivated postdoctoral research fellows to work on structural determination of dengue viral RNA and circular mRNA based therapeutics.

Responsibilities:

• Produce the RNA fragments in the UTR regions of dengue virus and determine their structures
• Develop a simple and efficient circular RNA production method
• Write project reports and scientific papers for publication
• Present research findings in relevant seminars and conferences

Requirements:

• PhD in biochemistry, molecular & cell biology, virology or related field
• Practical experiences in protein chemistry and/or RNA biology
• Good publication record
• Competent in scientific writing
• Strong problem-solving skills and attention to details
• Ability to work independently and as part of a team in a fast-paced research environment

Singapore is an excellent environment to do research with many research groups close by in Biopolis [https://www.a-star.edu.sg/imcb]. A*STAR offers highly competitive salaries with benefits including housing allowance and 1-3 months performance bonus.

Interested applicants should send a CV and three confidential letters of reference to: Prof. Haiwei Song (Email: haiwei@imcb.a-star.edu.sg), Institute of Molecular and Cell Biology, A*STAR, Singapore.  

[Post Date: March 18, 2023]

Research Fellow opportunity in the Rossjohn Lab, Monash University, Australia

View the Job Posting Here

Description:

Research Fellow opportunity in the Rossjohn Lab!

Prof. Jamie Rossjohn, FRS, NHMRC Investigator Fellow, is seeking research fellows to join the research group at Monash Biomedicine Discovery Institute, Clayton campus, Melbourne, Australia. The selected candidates will work in the field of T cell recognition specifically working on gamma delta T cells. The Rossjohn Laboratory, as part of a broad collaborative network that includes lead national and international researchers, has provided profound insight into T-cell immunology, specifically defining the basis of key immune recognition events by T-cells. The laboratory has notably pioneered our understanding of lipid-based immunity by the innate Natural Killer T-cells (NKT) and the role of MAIT cells in recognizing vitamin B metabolites. For more details on the research themes, fellowships awarded and publication outputs see, https://rossjohnlab.com/

Applicants should hold a PhD in Biochemistry, Molecular Biology, Structural Biology or Immunology with an interest in T cell recognition, Protein Chemistry, Crystallography or Immune Cell Biology. Experience in a number of the following areas would be an advantage:

1) Molecular Biology: site-directed mutagenesis

2) Protein Biochemistry- production, purification and analysis: E. coli, yeast, insect cells and/or mammalian expression systems (including cell culture techniques), chromatography, crystallography, proteomics

3) Cellular Immunology: tissue culture and flow cytometry;

4) Technologies: SPR, SAXS, Cryo-EM

Candidates with a promising track record in the relevant areas and a proven publication record in international journals are encouraged to apply. Appointment will be made at a level appropriate to the successful applicant’s qualifications, experience and in accordance with classification standards for Level A.

Salary range: Level A $94,970 -$101,944 plus 17% superannuation 

Duration:   1 year in the first instance               

Location:   Clayton Campus

Please direct all enquiries to Jennifer Huynh:  jennifer.huynh@monash.edu

[Post Date: March 15, 2023]

Postdoctoral Fellow - Structural Biology Approaches to Develop a Novel Diabetes Mellitus Therapeutic

View the Job Posting Here

Description:

Job Ref:

10020584

Location:

Monrovia, CA 91016

Category:

Postdoctoral Fellowships

Job Type:

Full-time, Days

Shift:

Days

[Post Date: March 14, 2023]

Scientist, Structural Biology

View the Job Posting Here

Description:

We have an open position in structural biology at Beam Therapeutics (Cambridge-MA). Join us and help develop cutting-edge technologies for gene editing.

Please apply here: https://beamtx.com/jobs/job/bthc-22rep-029-scientist-structural-biology/?gh_jid=6544772002

Position Overview 

We seek a highly skilled and innovative scientist to join Beam’s platform technology development group. This position is focused on structural biology that supports the development and engineering of novel gene editing proteins. The candidate should have a deep understanding and experience in cryo-electron microscopy and X-ray crystallography methods and broad knowledge of protein biochemistry and biophysics. 

Primary Responsibilities: 

• Independently design and execute cryo-EM and/or X-ray crystallography projects to study the mechanism of action for novel gene editing enzymes and other therapeutically relevant proteins 
• Prepare cryo-EM grids, collect data, and determine the structures for the protein-protein or protein-DNA/RNA complexes of interest. Earlier stage work, including molecular cloning and protein production, will be carried out by other scientists, but the candidate may remain involved if a project-specific need arises 
• Protein crystallization and structure determination of the proteins and protein-DNA/RNA complexes of interest. 
• Lead or contribute to protein engineering and construct optimization by providing structural biology insights 
• Closely collaborate with other platform scientists to drive the timely hypothesis-to-test cycle for the discovery and optimization of novel gene editing enzymes 
• Communicate scientifically rigorous structural biology findings via verbal and written communications, visualizations, and presentations, mainly to non-structural biologists 
• Maintain clear and accurate records of experimental methods and results 

Qualifications : 

• A Ph.D. in Structural Biology, Biochemistry, Biophysics, or equivalent, with expertise in cryo-EM or X-ray crystallography 
• Extensive knowledge in Structural biology, protein biochemistry, and protein engineering. 
• Aptitude with detailed structural analyses and integration of structural observations into subsequent construct engineering and optimization 
• Computational modeling experience is not a must but will be a significant plus 
• Experience with gene editing proteins (e.g., CRISPR/Cas9) will be a significant advantage 
• Demonstrated ability to work independently in a fast-paced and dynamic environment 
• Ability to adapt to increasing scope and complexity of work brought on by growth/change

[Post Date: March 14, 2023]

Senior Scientist/Scientist II, Structural Biology

View the Job Posting Here

Description:

We are seeking an experienced and motivated structural biologist to join the Protein Sciences and Lead Discovery team at Kymera Therapeutics.  As part of a dynamic team, the successful candidate will provide critical structural support (both x-ray crystallography and cryo-electron microscopy) for the identification and optimization of ligands to novel and proprietary E3 ligases as well as “undruggable” proteins of interest and will both conduct internal and drive external experiments to advance projects toward their goals. Kymera is advancing the field of targeted protein degradation, accessing the body’s innate protein recycling machinery to degrade rather than inhibit dysregulated, disease-causing proteins. This position will also play an important role in the progression of these binders to degraders. The successful candidate will work in a fast-paced and highly matrixed discovery environment requiring scientific rigor, organized and independently driven work, and exceptional attention to detail. 

Kymera Therapeutics is a publicly listed, clinical stage biotechnology company pioneering the field of targeted protein degradation (TPD) to bring life-changing medicines to patients that need them. Kymera’s Pegasus™ TPD platform harnesses the body’s natural protein recycling machinery to degrade disease-causing proteins, with a focus on undrugged nodes in validated pathways currently inaccessible with conventional therapeutics. As we work toward becoming a fully-integrated biopharmaceutical company, we are growing and strengthening organizational capabilities and evolving our culture. As a result, Kymera has been recognized by both the Boston Globe and the Boston Business Journal as one of Boston’s top workplaces.

In 2023, we plan to continue to advance our leadership in TPD and enhance our capabilities to deliver on the potential of inventing a new class of protein degrader medicines for patients. Kymera is rapidly advancing four clinical stage programs in oncology and immunology, and is positioned to deliver one additional Investigational New Drug Applications (IND) annually. We are also actively advancing a broad pipeline of preclinical programs where TPD has the potential to provide a best-in-class approach, both internally and in collaboration with our partners Sanofi and Vertex Pharmaceuticals.

Responsibilities:

• As a member of the protein sciences and lead discovery team, lead protein sciences and structural biology efforts to identify, validate, and fully characterize small molecule ligands and progress to targeted protein degraders.
• Contribute to the strategy for bringing novel E3 ligase and oncology/immunology targets to the Kymera portfolio.
• In collaboration with chemistry, biology, and platform teams, characterize binary and ternary complex formation and establish SAR to rapidly drive the hit finding, hit-to-lead, and lead optimization process.
• Deliver data, contribute to critical data evaluation, and provide strong discipline leadership to project teams.
• Augment our toolbox of structural biology techniques to address the specific needs of targeted protein degradation drug discovery.

Qualifications:

• PhD in Structural Biology or related discipline.
• 1-3 years of biotech/pharma industry experience with a track record of hit-finding, hit-to-lead, and lead optimization towards delivering small molecule development candidates is a plus.
• Experience working with CROs is preferred.
• Extensive knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, crystallization, structure determination and analysis.
• Experience in single particle cryo-EM workflow including grid freezing and screening, data collection and processing, three-dimensional reconstruction and model building.
• General knowledge of signaling pathways, protein homeostasis, and regulation of gene expression in a diverse disease context. Experience in targeted protein degradation or molecular glues is a plus. 
• Excellent presentation skills (written and oral) that enhance team-based delivery of results.
• Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment.
• Skills in managing multiple projects and capability to prioritize.

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics.

[Post Date: March 14, 2023]

Postdoc University of South Alabama

Description:

Applications from highly qualified candidates are invited for postdoctoral positions in my lab at the University of South Alabama in Mobile, AL. There are several NIH-funded projects: One is an ongoing project to elucidate molecular mechanisms underpinning the cephalosporin resistance of Neisseria gonorrhoeae conferred by mutated penicillin-binding protein 2 (PBP2). Another is a structure/function analysis of PlzA, a cyclic-di-GMP binding protein from the Lyme disease spirochete, Borreliella burgdorferi, to understand its biological roles in the enzootic cycle of the pathogen. Finally, there is a project to develop a lead compound against familial hypercholesterolemia.

Projects entail site-directed mutagenesis, cloning, purification and crystallization of proteins, collecting diffraction data, solving structures by X-ray crystallography, and various biophysical techniques (ITC, fluorescence spectroscopy). Investigations using cryo-EM are also planned.

Qualifications: Candidates should hold a PhD in biochemistry or chemistry, with a strong background in molecular biology and protein crystallography. For the PBP2 project, experience with enzyme kinetics is preferred.

To apply: Please send cover letter and CV directly to me by email to cdavies@southalabama.edu. Informal enquiries by email are welcome.

[Post Date: March 14, 2023]

NIH Postdoc fellowship opportunity at NIEHS in NC

Description:

Fully Funded Postdoctoral Position at the NIH

 Molecular Mechanisms of RNA Regulation

National Institute of Environmental Health Sciences (NIEHS)

National Institutes of Health (NIH)

Research Triangle Park, North Carolina

 A fully funded postdoctoral position is available in Dr. Traci Hall’s lab at the NIEHS/NIH in North Carolina. We are looking for people who are excited to use structural biology to discover how genes are regulated at the RNA level. We combine molecular, biochemical, and structural approaches to determine how RNA regulatory proteins/enzymes select specific targets and what happens when they engage their targets. Better yet, what happens when multiple proteins work together on RNA targets?

 We are seeking a postdoctoral fellow who has demonstrated success in structural biology (X-ray crystallography, NMR, cryo-electron microscopy) or a biochemist/biophysicist whose background is in RNA biology, enzymology, and macromolecular complex formation. Please see our recent publications for examples of our approaches: Molecular Cell 82:4049, Nucleic Acids Research 50:536).

We enjoy a stimulating environment, surrounded by interactive colleagues. Our group is part of the Epigenetics & Stem Cell Biology Laboratory, a diverse department applying different approaches to understanding epigenetic gene regulation.  In addition, our lab is adjacent to other structural biology groups, and we share outstanding facilities, including crystallization and X-ray facilities, regular synchrotron access, and a newly established Cryo-EM Core Facility.  Furthermore, the Research Triangle area has vibrant RNA and structural biology communities. Together these groups provide outstanding mentoring, community, and resources.

 Qualifications:

Candidates must possess a Ph.D. degree, strong communication skills, and publications that indicate a record of accomplishment. Candidates must also have fewer than five years of prior postdoctoral experience.

 To apply: Please send an email to Traci Hall (hall4@niehs.nih.gov) including

(1)  Cover letter that explains your background and why you want to join our lab

(2)  CV with publications

(3)  Names and contact information for three references.

Applications will be reviewed as they are received and until the position is filled.

 Website:  Macromolecular Structure Group - mRNA Stability & Translation

The NIH is dedicated to building a diverse community in its training and employment programs.

[Post Date: March 14, 2023]

Postdoc Macromolecular Structure group of i3S - Instituto de Investigação e Inovação em Saúde

Description:

We are looking for a highly motivated post-doc to join the Macromolecular Structure group of i3S - Instituto de Investigação e Inovação em Saúde (https://www.i3s.up.pt/research-group.php?groupid=113) in Porto, Portugal. The position, funded for up to 13 months, is expected to start in May 2023.

Building on our recent work (1-6), the project aims to develop direct anticoagulants against alternative targets in the blood coagulation cascade that have not been clinically exploited to date or represent a completely unexplored mechanism of intervention.

Informal inquiries can be addressed to Jorge Ripoll-Rozada (jorge.rozada@ibmc.up.pt) or Pedro J.B. Pereira (ppereira@ibmc.up.pt).

Please note that applications will be considered ONLY if submitted (together with ALL accompanying documentation) before 2023/03/31, using the online tool at https://dozer.i3s.up.pt/applicationmanagement/#/addapplications/ResearcherFTC_Proj2020i3S06032023.

Further information: https://dozer.i3s.up.pt/fileupload/downloadfile/viewpdfnewtab/72182470deba408df576958ce5c5befa (in Portuguese) or https://dozer.i3s.up.pt/fileupload/downloadfile/viewpdfnewtab/5efe13569f63a911df16b39ab7bd8f3a (in English).

1 - Thompson, R.E.; Liu, X.; Ripoll-Rozada, J.; Alonso-García, N.; Parker, B.L.; Pereira, P.J.B.; Payne, R.J. (2017) Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors. Nature Chemistry 9, 909-917. DOI: 10.1038/nchem.2744

2 - Watson, E.; Liu, X.; Thompson, R.; Ripoll-Rozada, J.; Wu, M.; Alwis, I.; Gori, A.; Loh, C.-T.; Parker, B.; Otting, G.; Jackson, S.; Pereira, P.J.B.; Payne, R. (2018) Mosquito-derived anophelin sulfoproteins are potent anti-thrombotics. ACS Central Science 4, 468-476. DOI: 10.1021/acscentsci.7b00612

3 - Watson, E.E.; Ripoll-Rozada, J.; Lee, A.C.; Wu. M.C.L.; Franck, C.; Pasch, T.; Premdjee, B.; Sayers, J.; Pinto, M.F.; Martins, P.M.; Jackson, S.P.; Pereira, P.J.B.; Payne, R.J. (2019) Rapid Assembly and Profiling of an Anticoagulant Sulfoprotein Library. Proceedings of the National Academy of Sciences of the USA 116, 13873-13878. DOI: 10.1073/pnas.1905177116

4 - Calisto, B.M.; Ripoll-Rozada, J.; Dowman, L.J.; Franck, C.; Agten, S.M.; Parker, B.L.; Veloso, R.C.; Vale, N.; Gomes, P.; de Sanctis, D.; Payne, R.J.; Pereira, P.J.B. (2021) Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chemical Biology 28, 26-33. DOI: 10.1016/j.chembiol.2020.10.002

5 - Agten, S.M.; Watson, E.E.; Ripoll-Rozada, J.; Dowman, L.J.; Wu, M.; Alwis, I.; Jackson, S.; Pereira, P.J.B.; Payne, R.J. (2021) Potent trivalent inhibitors of thrombin through hybridization of salivary sulfopeptides from hematophagous arthropods. Angewandte Chemie International Edition 60, 5348-5356. DOI: 10.1002/anie.202015127

6 - Dowman, L.J.; Agten, S.M.; Ripoll-Rozada, J.; Calisto, B.M.; Pereira, P.J.B.; Payne, R.J. (2021) Synthesis and evaluation of peptidic thrombin inhibitors bearing acid-stable sulfotyrosine analogues. Chemical Communications 57, 10923-10926. DOI: 10.1039/d1cc04742f

[Post Date: March 14, 2023]

Postdoc Positions Available TU Dortmund University

Description:

Job opening for two postdoctoral positions at the TU Dortmund University, Dortmund, Germany.

The lab of Daniel Rauh at the TU Dortmund University (https://www.rauhlab.de/, https://twitter.com/ddhdortmund) is currently looking for two postdoctoral
fellows to join our team. The positions are available immediately, initially for 1 year, but with the possibility of further extension until 2026.
Payment and benefits are based on the TVöD (wage agreement for public service personnel) guidelines (100 %, EG 13 or 14 TV-L – depending on prior
experience).

We are looking for experts in protein expression in insect and mammalian cells as well as in structural determination via protein X-ray crystallography
and cryoEM. The projects will deal with the expression, purification, and structural characterization of receptor tyrosine kinases (RTKs) and the effect of
mutations and drug resistance in cancer. Successful candidates will be highly motivated to succeed, able to think critically, and can work both independently
and collaboratively. Good verbal and written communication skills are essential.

To better understand acquired resistance and develop more effective inhibitors, the Rauh Lab employs multiple techniques such as protein X-ray
crystallography, structure-based design, organic synthesis, and biochemical and cellular compound screening. Moreover, we strive to narrow the gap
between academic research and practical pharmaceutical applications.

In case you are interested in the advertised position, please send the usual documents (CV, a short description of your prior experience and motivation,
as well as contact information of 2 referees in a single pdf file to office-cb.ccb@tu-dortmund.de), and don`t hesitate to contact me in case of
questions.

[Post Date: March 14, 2023]

Postdoc for Noncoding RNAs-Protein Complexes

View the Job Posting Here

Description:

The Nakanishi lab at The Ohio State University (https://u.osu.edu/nakanishilab/) is looking for a highly motivated and skilled postdoc.  Our group aims to understand how noncoding RNAs work with their cognate proteins to regulate gene expression.  We study human macromolecules involved in critical cellular events in normal conditions and diseases.  The successful candidates must have a Ph.D. and expertise in X-ray crystallography.  Practical skills (protein production on a large scale, protein purification using FPLC, crystallization, data collection, and structure determination) are essential.  Experience in Cryo-EM is advantageous.  For more information, please visit our website.

The position is available immediately.  The annual salary wage is $48,000 - 60,000 for three years (renewable).  The weather in Columbus is stable, and the living cost is reasonable.  So, postdocs can focus on their research to build a successful career.

Interested candidates should send the following directly to nakanishi.9@osu.edu.

• CV including a publication list.
• One-page research statement including 1. the current work, 2. the reason for joining our group, and 3. the future goals after postdoc training.

• Contact information of three references.

[Post Date: March 14, 2023]

Postdoc Structureal Biology of Parasite Motility

View the Job Posting Here

Description:

We are looking for a post-doctoral fellow for a 2.5-year project (possible extension for up to 1 year) in my group at the Faculty of Biochemistry and Molecular Medicine (FBMM), University of Oulu, Finland. Alternatively, an exceptionally highly-qualified PhD student could be considered. The overall aim of my group is to understand the molecular mechanism of malaria parasite gliding motility. To reach this goal, we use a wide variety of structural biology and biochemical/biophysical methods. Our ongoing work is focused on (i) the polymerization and ATPase mechanism of actin, (ii) parasite actomyosin complexes, (iii) the structure and function of the glideosome-associated linker protein, and (iv) reconstructing the entire membrane-delimited motor complex in vitro for structural and functional studies. The exact project will be agreed upon based on the experience and interests of the successful candidate.

The candidate should have a PhD (or MSc if applying for a graduate student position) in a relevant field of science and have experience, or at least a keen interest, in all or several of the following:

- molecular biology and protein expression and purification

- biophysical and biochemical characterization of proteins and their complexes

- protein crystallography and/or cryo-EM

- light and/or electron microscopy

We welcome applications particularly from candidates willing and eligible to apply for competitive funding from national, European, and international sources.

Our research group is split between the FBMM in Oulu and the Department of Biomedicine, University of Bergen, Norway. Our laboratories and the available core facilities available have state-of-the-art equipment for molecular biology, protein biochemistry/biophysics, and electron and light microscopy. We have active collaborations for cryo-EM and cell biology/parasitology.

The project is funded by the Sigrid Jusélius foundation, and the candidate will receive a personal stipend (tax-exempt up to the limit defined by the Finnish tax authorities and subject to a compulsory pension insurance).

Informal inquiries and applications including a motivation letter, a CV with publication list, and contact information for 2-3 referees are to be sent to inari.kursula@oulu.fi. Applications will be considered until a suitable candidate has been identified. The starting date is as soon as possible.

Publications most relevant for the project:

Pires I, Hung YF, Bergmann U, Molloy JE & Kursula I (2022) Analysis of Plasmodium falciparum myosin B ATPase activity and structure in complex with the calmodulin-like domain of its light chain MLC-B. J Biol Chem in press, https://doi.org/10.1016/j.jbc.2022.102634

Vahokoski J, Calder L, Lopez AJ, Molloy JE, Kursula I & Rosenthal PB (2022) High-resolution structures of malaria parasite actomyosin and actin filaments. PLoS Pathog 18: e1010408.

Kumpula EP, Lopez AJ, Tajedin L, Han H & Kursula I (2020) Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation. PLoS Biol 17: e3000315.

Kumpula EP, Pires IP, Lasiwa D, Piirainen H, Bergmann U, Vahokoski J & Kursula I (2017) Apicomplexan actin polymerization depends on nucleation. Sci Rep 7: 12137.

Pospich S, Kumpula EP, von der Ecken J, Vahokoski J, Kursula I & Raunser S (2017) Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability. Proc Natl Acad Sci USA 114: 10636-10641.

Jacot D, Tosetti N, Pires IP, Stock J, Graindorge A, Hung YF, Han H, Tewari R, Kursula I & Soldati-Favre D (2016) An apicomplexan actin-binding protein serves as a connector and lipid sensor to coordinate motility and invasion. Cell Host Microbe 20: 731-743.

More info:

Group webpages in Oulu: https://www.oulu.fi/en/research-groups/molecular-mechanisms-parasite-motility and Bergen: https://www.uib.no/en/rg/inari

Selected publications: https://www.uib.no/en/rg/inari/149298/our-publications

FBMM Oulu: https://www.oulu.fi/en/university/faculties-and-units/faculty-biochemistry-and-molecular-medicine

[Post Date: October 26, 2022]