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Crystallography related career opportunities, post docs and related positions in the crystallography community. If you wish to place your job opportunity on the Hampton Research website, submit the details to tech@hrmail.com.


Two Postdoc Positions Department of Biological Chemistry and Pharmacology at the Ohio State University

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Description:

Two postdoctoral fellow positions are immediately available in Tianmin Fu’s laboratory in the Department of Biological Chemistry and Pharmacology at the Ohio State University. The positions are supported by NIH and departmental funding to study molecular mechanism of signaling protein assembly and regulation in inflammation and neurodegenerative diseases. Fu Lab aims to understand the logic of cell signaling across membrane using a multidisciplinary approach including biochemical reconstitution, cryo-electron microscopy, X-ray crystallography, cell biology and pharmacology.

Successful candidates are expected work closely with Dr. Fu in the lab to design and carry out experiments, analyze, organize, and present data in written form and to meetings, and to write papers and grants.

Salaries, stipend, and benefits are highly competitive and commensurate with university policy and NIH guidelines.

The Ohio State University (OSU) is located in Columbus, the capital of Ohio, a fast-growing city in northeast US.

Postdoctoral fellow candidates should hold a Ph.D. degree (or will complete one soon) in structural biology, biochemistry, biophysics, molecular biology, or closely related biological science areas. Prior experiences with membrane protein purification, or cryo-electron microscopy are a plus but not required.

Interested candidates should send a cover letter summarizing their research interests and CV with a publication list and names and contact info of three references (preferably in a single PDF) to fu.978@osu.edu. Informal inquiries are welcome. 


[Post Date: July 9, 2020]


Research Associate in Structural Biology, University of Cambridge - Cambridge Institute for Medical Research - Clinical Neurosciences

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Description:

We are seeking an enthusiastic and motivated Postdoctoral Research Associate to join the group of Dr Janet Deane at the Cambridge Institute for Medical Research.  Our team uses multidisciplinary approaches to investigate the molecular mechanisms underlying neurodegenerative disease.  We have recently received Wellcome Trust funding to study how altered processing of glycosphingolipids causes mistrafficking of membrane proteins.  We are looking for an experienced structural biologist to use protein crystallography and/or cryo-EM to study how specific glycosphingolipids interact with membrane protein targets.  The ultimate goal of this work is to understand how these complexes may direct trafficking of proteins to the plasma membrane and other cellular compartments.  The CIMR is based on the Cambridge Biomedical Campus and possesses excellent core facilities and laboratory space.

The successful candidates must: 1) hold a PhD in Biochemistry, Structural Biology or a relevant subject; 2) have a proven track record of generating publication-quality data; 3) be able to think creatively and have an enthusiasm for finding new approaches to tackle scientific problems; 4) have good interpersonal skills and be able to communicate their work clearly in both formal and informal settings, and 5) have great attention to detail and excellent record keeping.

This research project will require the candidate to have extensive experience in biochemistry and structural biology.  Additional experience in mammalian expression systems, lipid biochemistry or biophysical techniques (such as isothermal titration calorimetry) would be highly advantageous.  Due to the multidisciplinary and supportive nature of the laboratory there will be opportunities for candidates to develop their professional skills and to be trained in additional experimental techniques.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/25425

For informal enquiries please contact Dr Janet Deane at jed55@cam.ac.uk

Please quote reference SD22680 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.


[Post Date: July 9, 2020]


Research Technician EMBL Grenoble, France

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Description:

A Research Technician position is available in the High Throughput Crystallization Laboratory at EMBL Grenoble

The HTX lab is one of the largest platforms for automated macromolecular crystallization screening in Europe and is offering services through Instruct and the EC-funded project iNEXT-Discovery. The Marquez Team has developed stream-lined pipelines for fragment screening by X-ray crystallography based on the CrystalDirect technology for automated crystal harvesting and the CRIMS software. These pipelines are applied to study targets of biotechnological and biomedical relevance. The successful candidate will contribute towards the operation of the HTX facility, the development of innovative methods in protein crystallography and will participate in research projects. Under specific circumstances candidates with a PhD and publications who wish to change their career path can also be considered. See details attached.

Applications should be submitted through the www.embl.de/jobs/ portal.

Deadline for applications is August 15th.

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[Post Date: July 7, 2020]


Crystallography, CRELUX, Martinsried, Germany

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Description:

A new opportunity has arisen for an experienced Crystallographer to join our growing X-Ray Crystallization Group. This involves the hands on work as well as an up to date knowledge of modern crystallization techniques and standard crystallographic software.

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[Post Date: July 6, 2020]


PostDoctoral Position in Membrane Protein Structural Biology at USC, Los Angeles

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Description:

The position is available starting January 2021 in the Department of Biological Sciences at the University of Southern California and is initially limited to 2 years, with possible extension.

Our research focuses on the structural biology of important membrane proteins, using single particle cryoEM and X-ray crystallography. We are working in close collaboration with the group of Prof. Vadim Cherezov (USC) on the structural biology of GPCRs. External collaborations include the group of Prof. Dirk Slotboom (Univ. of Groningen) and Prof. K. Chris Garcia (Stanford University).

USC has a suite of research facilities and is in the process of installing a new CryoEM center:

  • Electron microscopy suite: Titan Krios with GIF Quantum energy filter and K3 detector, Glacios with Falcon 4 detector, Talos Arctica with CCD/side entry holder for NS and screening
  • Core facility for insect- and mammalian cell expression
  • High performance computing for data processing/analysis

Qualified candidates must have a Ph.D. degree with a solid background in structural biology and biophysics/biochemistry. Previous work with membrane proteins is a plus. A successful candidate is expected to be highly skilled and self-motivated and is willing to work in a collaborative environment. The Postdoctoral salary depends on qualifications and relevant experiences according to USC standards.

Interested candidates should apply directly with Cornelius Gati at cornelius.gati[at]gmail.com. Please attach a cover letter, Curriculum Vitae, research statement, publication list and a reference letter. The deadline for the application is September 30th 2020.

Current group website: https://gati-lab.slac.stanford.edu/

Recent work from our group includes:

H Shaye, A Ishchenko, JH Lam, GW Han, L Xue, P Rondard, JP Pin, V Katritch, C Gati*, V. Cherezov*

Structural basis of the activation of a metabotropic GABA receptor. Nature. 2020.

S Rempel, C Gati*, M Nijland, C Thangaratnarajah, A Karyolaimos, JW de Gier, A Guskov*, DJ Slotboom*.

A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds. Nature. 2020.


[Post Date: July 2, 2020]


Postdoc position in the Fesik Lab at Vanderbilt University

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Description:

A postdoc position is available in the laboratory of Dr. Stephen Fesik (https://lab.vanderbilt.edu/fesik-lab/) for a structural biologist with experience in protein NMR or X-ray crystallography.  Responsibilities will include protein expression/purification, conducting fragment screens using NMR, and all aspects of x-ray crystallography, including preparation of protein-inhibitor complexes, crystallization, home/synchrotron data collection, and structure determination. Experience in cloning, site-directed mutagenesis, and the use of robots are highly preferred.  The ideal candidate should be self-motivated and be able to communicate effectively in a highly collaborative environment.


[Post Date: July 1, 2020]


Group Leader – X-ray imaging of biological samples, EMBL Hamburg

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Description:

We are seeking to recruit a group leader to develop X-ray imaging applications in the life sciences towards a future user facility.

EMBL Hamburg has pioneered the use of synchrotron radiation in the Life Sciences and has provided service facilities for the use of X-rays in Structural Biology for decades on the DESY campus, Hamburg, Germany. At present, the EMBL Integrated Facility for Structural Biology provides access to structure determination pipelines employing crystallography and/or small-angle X-ray scattering to a large international user community.

EMBL’s future scientific directions, Molecules to Ecosystems, include a vision to advance our understanding of ecosystems at the molecular level, applying expertise in molecular biology to study life in its natural context. New research areas will focus on applying experimental, computational and theoretical approaches to study at multiple levels (molecules, cells, tissues and populations) how organisms interact with each other and respond to environmental change.

Inspired by ground-breaking experiments in the field of X-ray imaging of biological samples, scientists from EMBL have recently started to explore the possibilities of making high-energy X-ray imaging accessible to a wider biological scientific community. Here, we are looking for a candidate with the ability to expand the research and service portfolio of the EMBL Hamburg Unit into X-ray imaging applications. While the current synchrotron PETRA III already provides excellent conditions, the planned upgrade of the on-site synchrotron ring in Hamburg to PETRA IV will open unprecedented new opportunities for X-ray imaging as well.

Your role

  •    Establish an independent and innovative research program towards new approaches in X-ray imaging of biological samples, encompassing experimental, technical or computational developments.
  •    Facilitate experiments in X-ray based and correlative imaging of biological materials, ranging from cells to organoids, organs and organisms, using existing facilities at EMBL and other relevant research infrastructures.
  •    Develop concepts for a future integrated user facility for biological X-ray imaging; participation in the overall planning for facilities at the future PETRA IV synchrotron.

You have

  •    A PhD in a relevant research area.
  •    Profound expertise and track record in X-ray based imaging of biological material, with a particular interest in methodological developments. Additional expertise in correlate imaging approaches would be advantageous.
  •    Strong motivation to work at highly collaborative and multidisciplinary environment of EMBL.
  •    A concise research plan with clearly outlined, original and ambitious research goals.


[Post Date: July 1, 2020]


Beamline scientist position - MX3 beamline at the Australian Synchrotron

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Description:

We need a new beamline scientist in the MX team at the Australian Synchrotron in Melbourne. This position is on the new microfocus MX3 beamline which is currently being designed and is scheduled for first users July 2023. This is a new 4-year fixed-term position in the MX3 build team. There is a potential for this role to contribute in the post-implementation phase of the project and possibly be a long-term appointment.


[Post Date: July 1, 2020]


Research Technician Position, Baylor College of Medicine, Houston, Texas

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Description:

A RESEARCH TECHNICIAN POSITION is available in the Advanced Technology Core for Macromolecular X-ray Crystallography at Baylor College of Medicine in Houston, TX. The mission of the X-ray Core is to assist basic scientists and clinicians in finding structure solutions in order to develop novel treatments against unmet human diseases. The successful applicant will assist with the robotic crystallization screening and crystal optimization of proteins and protein-drug complexes. This is an entry level staff position that does not require prior experience with crystallization or structure analysis methods. Experience with protein expression and/or purification is an advantage. Salary is commensurate with experience and is in addition to a generous fringe benefit package.

Applicants must have a bachelor's degree in Biochemistry, Chemistry, or in one of the Natural Sciences, and must possess excellent verbal communication and writing skills. To apply, please send a current CV with relevant course work taken, a description of research experiences, and contact information for three referees to Dr. Sukyeong Lee, Associate Professor and Director of the X-ray Core Laboratory.


[Post Date: June 29, 2020]


Scientist Merck KGaA, Darmstadt, Germany

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Description:

Your Role:

You will play an important role as scientist in our Healthcare research programs by designing, planning and executing biophysical studies and providing data on molecular interactions to drug discovery projects. Specifically, within our interdisciplinary biophysical and structure biology team, you will design and perform the biophysical characterizations of recombinant target proteins with respect to binding of small molecules or antibodies and in order to enable the generation of protein-ligand complex structures. Your work includes the generation, analysis, interpretation and reporting of experimental data. You will present results to internal and cross functional project teams. Your role will also involve collaboration with various partners across all functions of our research organization. As further important part of your work you will participate in external collaborations for the support of biophysical and structural studies. You will also be involved in the assessment and implementation of novel technologies and in the evaluation of innovative drug targets.

Who You Are:

  • You are holding a Ph.D. in Biophysics, Structural Biology, Biochemistry, Chemical/Biochemical Engineering, Applied Chemistry, or related field, and you have gained substantial practical lab experience in an academic, biopharmaceutical or biotechnological setting.
  • You have expertise in characterizing recombinant proteins by biophysical methods and experiences with the determination of intermolecular binding affinities, thermodynamics and kinetics.
  • You have solid experience in protein structure determination (e.g. by X-ray crystallography or cryo-EM, structure refinement) and computational structure analysis.
  • You have strong oral and written communication skills in English and like to work in cross functional, intercultural teams. You can summarize and present scientific facts in a sound, concise and structured way.
  • You have first experiences in the supervision and/or training of technical assistants or students, and you can routinely set up workplans keeping focus on project objectives and timelines.
  • Research experience in the fields of oncology, immuno-oncology or immunology is advantageous


[Post Date: July 1, 2020]


PostDoc Syun-Ru Yeh Laboratory at Albert Einstein College of Medicine, New York

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Description:

A NIH-funded postdoctoral position in structural biology is available immediately in the Syun-Ru Yeh Laboratory at Albert Einstein College of Medicine, New York. The postdoctoral fellow will take a lead in elucidating structure and function relationships in two classes of human immunosuppressive proteins, indoleamine 2,3-dioxygenase and tryptophan dioxygenase. The postdoctoral fellow will join an exciting program with a focus on biochemistry and spectroscopy-guided crystallography.  

The successful applicant must have demonstrated experience in chemistry, biochemistry, biophysics or closely related fields. Expertise in spectroscopy, x-ray crystallography and/or computational modeling is a plus. Applicants should provide a CV and a cover letter justifying their suitability and interest in the position. Applicants should also arrange to have three letters of reference sent to Dr. Syun-Ru Yeh (syun-ru.yeh@einsteinmed.org).

Albert Einstein College of Medicine is located in New York in a scenic Bronx campus that includes comfortable, affordable housing in an area rich with recreation and entertainment. The scientific environment provides outstanding research training opportunities.


[Post Date: June 29, 2020]


Crystallographer position at Eternity Bioscience

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Description:

Eternity Bioscience Inc. in Cranbury, New Jersey, USA, is a discovery research subsidiary of Jiangsu Hengrui Medicine Co., Ltd. of China. Our mission is to deliver high quality and translational preclinical drug candidates for critical medical needs. The company is seeking a well-qualified structural biologist to join its drug discovery team. The successful candidate will be proficient in working independently and collaboratively as part of multidisciplinary project teams and have the capacity to quickly adapt to project priority changes.

Job Description:

1.   Perform necessary duties including gene construct design, high throughput recombinant protein expression, purification and characterization, target/drug complex crystallization screening, remote-controlled (and occasional in-person) collection of X-ray diffraction data, and high-resolution atomic structure determination.

2.   Deliver high-quality and timely structure data to project teams to enable iterative structure-based drug design.

3.   Present the work clearly in internal project meetings.

Basic Requirements:

1.   PhD degree in structural biology, with drug discovery research experience desirable.

2.   Proficiency in the workflow from gene construct design to atomic structure determination.

3.   Knowledge in structure-based drug design using modern modeling and design tools.

4.   Ability to work in a diverse team setting and collaborate effectively on complex projects.

5.   Excellent communication, interpersonal, and organizational skills. Bilingual in English and Mandarin is a plus.

Prospective candidates are encouraged to visit the following link for more information: www.eternitybioscience.com.

As a well-funded biotech company, we pay highly competitive salaries and a comprehensive benefits package. Interested applicants are encouraged to submit their CV to the following email address: zhuangl@eternitybioscience.com.


[Post Date: June 29, 2020]


Senior Scientist I, Protein X-ray Crystallography

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Description:

Company overview:

AbbVie (NYSE:ABBV) is a global, research-driven biopharmaceutical company committed to developing innovative advanced therapies for some of the world’s most complex and critical conditions. The company’s mission is to use its expertise, dedicated people and unique approach to innovation to markedly improve treatments across four primary therapeutic areas: immunology, oncology, virology and neuroscience. In more than 75 countries, AbbVie employees are working every day to advance health solutions for people around the world.

Job description:

The Protein Crystallography Group at AbbVie Headquarters in Lake County, Illinois is seeking a highly motivated scientist to join our Structure-Based Drug Discovery team. The ideal candidate should have extensive hands-on experience in modern X-ray Crystallography techniques and computational methods of molecular structure analysis. As part of multidisciplinary teams, the Scientist will utilize fragment-based strategies to identify ligands and provide insight to advance drug discovery targets through structure-based design. The successful candidate will contribute to drug discovery projects across the portfolio of AbbVie interests that also include therapeutic antibodies and novel biologics.


[Post Date: June 25, 2020]


Postdoc Positions in Du and Lü labs at Van Andel Institute

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Description:

A few joint postdoctoral positions are available in the laboratories of Dr. Juan Du and Dr. Wei Lü at Van Andel Institute. The Du lab and Lü lab are interested in understanding how human body senses external stimuli, conveys the signals to the brain and generates responses via ion channels. To address these fundamental questions, our lab uses a diverse set of approaches to study the structure and function of these ion channels by combining single-particle cryo-EM, patch-clamp electrophysiology, X-ray crystallography, and other functional approaches. The cryo-EM facility at Van Andel Institute host a Titan Krios equipped with a K3 camera, and a Talos Arctica equipped with a K2 camera.

Experience in structural biology, membrane protein biochemistry, or ion channel electrophysiology are preferred, but not required. Interested individuals should send a CV and a cover letter to Wei Lü (wei.lu@vai.org). For more information, please visit our lab website https://dululabs.com/


[Post Date: June 22, 2020]


Post-doctoral position in Structural Biology - Paris-Saclay University, INRAE

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Description:

A post-doctoral position in structural biology is available at the ChemSyBio team (Paris-Saclay University, INRAE, Micalis) headed by Dr Olivier Berteau. The project involves structure determination of novel metalloenzymes catalyzing post-translational modifications in peptides (ribosomally synthesized and post-translationally modified peptides, RiPPs) in order to decipher their mechanisms and enzyme substrate interactions.


We are seeking for a highly motivated post-doctoral fellow with a proven experience in structural biology. The candidate should have a PhD in structural biology and a good knowledge of crystallography software. He/She should have an experience in protein expression, purification, crystallization and the ability to work in a multi-disciplinary environment. Skills in molecular biology and physico-chemical techniques would be an asset.


Recent publications from our team include: Balty C et al. 2019 JBC; 294(40):14512-14525; Parent A. et al. 2018 J Am Chem Soc. ; 140(7):2469-2477.; Benjdia A et al. 2017 Nature Chemistry ; 9(7):698-707; Parent A. et al. 2016 J Am Chem Soc.; 138(48):15515-15518; Benjdia A. et al.2016 Chem Commun.; 52(37):6249-52; Benjdia A. et al. 2015 Nat Commun; 6:8377.


Access to state-of-the-art research facilities will be provided. Our laboratory (Micalis institute) is part of Paris-Saclay University and located near Paris. The position is offered for two years and the salary will be commensurate with experience.
Applications (including CV, description of your research activity indicating your relevant skills and reference letters) should be sent to Dr Alhosna Benjdia (alhosna.benjdia@inrae.fr) and Dr Olivier Berteau (olivier.berteau@inrae.fr).

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[Post Date: June 16, 2020]


Laboratory Research Specialist

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Description:

A full-time laboratory research specialist is available for investigating innate immune regulation by microbes (bacteria and viruses) and vaccine design.   We seek to understand 1) how microbes regulate innate immune activation, and 2) how this influences host response to infection.   Our goal is the development of safe and effective therapeutics for controlling infection, inflammation and disease.   We primarily use cryo-EM, X-ray crystallography and NMR along with complimentary biophysical and biochemical approaches to investigate molecular interactions of microbes and host. As part of the Vaccine Research Division at the Institute of Human Virology, we utilize a uniquely integrated translational research platform involving clinical, basic, and vaccine research sciences.

The Institute of Human Virology (IHV) was founded in 1996 to expedite scientific understanding of persistent human diseases, viral infection, induced cancers, and to develop therapeutic interventions that will improve the lives of patients with infectious diseases. The full-time faculty number more than 250 M.D., M.D./Ph.D. and Ph.D. professionals, as well as adjunct faculty in 9 African and 2 Caribbean nations. This multidisciplinary center integrates basic, epidemiologic, clinical and vaccine research and translates this research into the development of medical therapeutics and vaccines. The Clinical Care and Research Units, Basic Sciences, Cancer and Vaccine Research Divisions are all located within one building and directly adjacent to the University of Maryland medical school, hospital and Baltimore VA medical centers. This location provides convenient and direct access for patients as well as unique opportunities for translational research and therapeutic development.

Qualifications and Application Procedure: This position will include a range of activities including supporting I) benchtop experiments (e.g., cell culture, protein expression and purification and characterization), II) research data analysis, and III) lab operations. I am committed to the development and training of individuals from diverse and underrepresented backgrounds in science. Interested candidates should apply to the Laboratory Research Specialist (#2000009H) position posted at the University of Maryland, https://umb.taleo.net/careersection/jobdetail.ftl?job=2000009H&lang=en  

Applications will be reviewed until the position is filled.    


[Post Date: June 4, 2020]


Senior Group Leader - Protein Structure Group

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Description:

We are looking for a Structural Biologist to head up a group in the Protein Structure and Biophysics department.  Job ID:  67082

Role overview

 The Protein Structure and Biophysics department, within the R&D sector of UCB, comprises 4 sub-groups: Protein Production, Protein Structure, Protein Biophysics and Molecular Spectroscopy.

The Protein Structure Group provides support for projects from early stage mechanistic and structural understanding of new protein targets to contributions in confirming hit identification and cycles of design with CADD and medicinal chemistry groups.  The role is at the Senior Group leader level heading up the Protein Structure group, reporting into the Head of the Protein Structure and Biophysics department.  This is an excellent opportunity to develop the group, driving the scientific direction of the team and maximising the impact of structural biology on drug discovery projects.  You will be a high calibre, partly laboratory-based candidate, with extensive experience in protein crystallography, a detailed knowledge of single particle cryo-EM and knowledge of protein NMR.  A key aspect of the role will be to develop members of the team, building a culture of openness and integrity and ensuring operational efficiency.

 This role will be based in Slough, UK.


[Post Date: June 2, 2020]


Postdoctoral opportunities in structural biology of parasite signal transduction

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Description:

The Reese lab at UT Southwestern Medical Center is recruiting highly motivated postdocs to join our team studying the molecular mechanisms of signaling at the Toxoplasma-host pathogen interface. We take an interdisciplinary approach and combine methods from molecular genetics, cell biology, biochemical and biophysics to deeply interrogate Toxoplasma biology.

Current projects include:

  • Combining cell biology with innovative cryoET and XL-MS methods to determine structures of parasite complexes required for the biogenesis of the Toxoplasma parasitophorous vacuole
  • Cellular and biophysical studies (cryoET, cryoEM, X-ray crystallography) of signaling complexes essential to parasite invasion of mammalian cel
  • Structure-based drug discovery for inhibitors of kinases essential to the apicomplexan lytic cycle (that is, the parasites that cause the human diseases toxoplasmosis, malaria, and cryptosporidiosis).

This would be a great opportunity for someone with graduate training in molecular cellular biology or genetics to learn to integrate biophysics and biochemistry into their research. Those with strong biophysics training who would like to dive into work on an atypical model organism with strong medical relevance are also encouraged to apply. Applicants should hold a recent Ph.D. (or be within a year of receiving their Ph.D.). If interested, please send a CV with cover letter and contact information for 2-3 references to michael.reese@utsouthwestern.edu.

Members of the Reese lab have full access to outstanding shared facilities as UT Southwestern, including high-field NMR, X-ray crystallography (with regular synchotron access), and world-class cryoEM. UT Southwestern is highly collaborative institution located in the heart of Dallas, TX. Dallas is a diverse city that is fun and affordable, with great food and arts.

As an equal opportunity employer, UT Southwestern’s employment decisions are made without consideration of race, color, national origin, religion, sex, age, veteran status, or disability.​​


[Post Date: May 19, 2020]


Postdoctoral Research Associate Brookhaven National Laboratory

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Description:

The Biology Department has an opening for a Postdoctoral Research Associate to complement the efforts of the Quantitative Plant Science Initiative (QPSI) in the Biology Department of Brookhaven National Laboratory. We invite talented candidates to apply for this position to work on plant membrane proteins in particular metal transporters. The ideal candidate will carry out structural and functional investigation of metal transporters involved in nutrient uptake, stress responses, photosynthesis, and metal homeostasis. Structural and mechanistic understanding that underlies the physiological role of these membrane proteins will expand our knowledge base with which to manipulate bioenergy crops for improved adaptation to growth on marginal land. The successful candidate will also be expected to assist with developing a high-throughput platform for membrane protein production and characterization at small scale. An initial two-year appointment may be renewed for up to five years contingent on performance and availability of funds.


[Post Date: May 19, 2020]


Senior Crystallography Scientist Abingdon Evotec

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Description:

Evotec (UK) Ltd is currently seeking to add to its Structural Biology Department. The group works closely with our Discovery Chemistry Department and with clients to develop novel small molecule drugs. It is at the forefront of new science and technology, and is seeking to expand as business needs grow.


[Post Date: April 23, 2020]


Postdoctoral Research Associate (Structural Biology, X-ray Crystallography) The Hevener laboratory at the University of Tennessee Health Science Center

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Description:

The Hevener laboratory at the University of Tennessee Health Science Center invites applications from highly motivated and self-sufficient scientists for a full-time Postdoctoral Research Associate to support a multi-year, federally funded research project. The successful candidate must possess a Ph.D. in protein biochemistry, structural biology or a closely related discipline and have expertise in macromolecular x-ray crystallography. Additional skills in protein expression/purification and molecular cloning are desirable. Candidates must also possess strong oral and written communication skills, the ability to work both independently and as the member of a team, and a record of first author publications in structural biology. Learning opportunities for the successful candidate include training in enzymology, HTS assay design, virtual screening, and computer-aided methods in drug development.


The Hevener Laboratory at UTHSC focuses on the validation and characterization of novel infectious disease drug targets using both experimental and computational methods. This project focuses on a target in the bacterial fatty acid synthesis pathway and will involve x-ray co-crystallography and structure-guided lead optimization. UTHSC offers postdoctoral researchers a competitive salary and full benefits package. Negotiable release time will be permitted for the development of independent projects.


Application Process: For full consideration, please apply through https://uthsc.edu/hr/employment/ Post-Doctoral Fellow Positions #2000000IX, and submit the following items: a cover letter; full curriculum vitae; list of three references; and a summary of research experience. Review of applications begins on arrival and the search will remain open until the position is filled.


The University of Tennessee is an EEO/AA/Title VI/Title IX/Section 504/ADA/ADEA/V institution in the provision of its education and employment programs and services.

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[Post Date: May 11, 2020]