Image credit: Zhaoqian Wang, Ha V. Dang, Moushimi Amaya, Yan Xu, Randy Yin, Lianying Yan, Andrew C. Hickey, Edward J. Annand, Bethany A. Horsburgh, Peter A. Reid, Ina Smith, John-Sebastian Eden, Kai Xu, Christopher C. Broder, and David Veesler. Potent monoclonal antibody-mediated neutralization of a divergent Hendra virus variant. Proceedings of the National Academy of Sciences, Volume 119, Number 22, pages e2122769119, May 26, 2022. DOI: 10.1073/pnas.2122769119 Figure 4. (A)
Wang et al report the crystal structure of a Hendra virus variant (HeV-g2) head domain in complex with the Fab fragment of the neutralizing monoclonal antibody, hAH1.3 in a research article from the Proceedings of the National Academy of Sciences, Volume 119, Number 22, pages e2122769119, published May 26, 2022. The optimized crystals were obtained with the sitting drop vapor diffusion method at room temperature while using the Hampton Research Additive Screen. The final condition for the crystal was 22% v/v Tacsimate pH 7.0, 0.1 M Hepes pH 7.5, 0.1 M Lithium sulfate, and 5% v/v Polyethylene glycol 200.