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Crystallography related career opportunities, post docs and related positions in the crystallography community.
If you wish to place your job opportunity on the Hampton Research website, submit the details to
tech@hrmail.com.
Description:
A postdoctoral position is available at the University of Texas Medical Branch (UTMB) to study the structure and active conformations of membrane-associated blood coagulation protein and complexes.
Highly motivated candidates with experience in macromolecular structure analysis, molecular modeling and biophysics are encouraged to apply. Experience with linux computing systems and programming will be an advantage.
The Sealy Center for Structural Biology and Molecular Biophysics at UTMB, as well as the PI’s lab are fully equipped for state of the art structure determination of macromolecular complexes: http://www.scsb.utmb.edu/symposium/index.htm. UTMB is also part of the Gulf Coast Consortium: http://cohesion.rice.edu/centersandinst/gcc/ and the Texas Medical Center.
Interested candidates should send a CV including areas of expertise and interest, publications list, and names and contact information for 3 references to svmcphie@utmb.eduUTMB is an equal opportunity employer.
Svetla Stoilova-McPhie, PhD
Assistant Professor,
Department of Neuroscience and Cell Biology
Scientist, Sealy Centre for Structural Biology
and Molecular Biophysics
University of Texas Medical Branch at Galveston
301 University Boulevard, Galveston, Texas 77555-0620
[Post Date: July 21, 2010]
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Description:
The Paul Scherrer Institute is with 1300 employees the largest research centre for the natural and engineering sciences in Switzerland and a worldwide leading user laboratory. Its research activities are concentrated on the three main topics structure of matter, energy and environmental research as well as human health.
The Swiss Light Source (SLS) is one of the most advanced synchrotron radiation sources worldwide. The SLS operates two state-of-the-art undulator beam lines for protein crystallography, and a third, highly automated beam line located at a superbend magnet (X06DA). At beam line X06DA a crystallisation facility which is integrated with the beam line in order to allow for in situ X-ray diffraction screening is being implemented. The Macromolecular Crystallography Group is involved in several aspects of protein crystallography including the design and construction of new beam line components as well as various structural biology projects, especially in collaboration with the Biomolecular Research Group under the guidance of Prof. Dr Gebhard Schertler.
We are looking for a Crystallisation Facility Scientist.
Your tasks
You will lead our efforts to extend and automatise the high-throughput crystallisation facility and its integration with beam line X06DA at the Swiss Light Source and build up the user programme of this facility. In collaboration with scientists and engineers of the SLS MX-group you will further develop the in situ X-ray diffraction screening capabilities of the facility and coordinate its integration with the sample data base. Further tasks are the implementation of crystallisation in lipidic cubic phase as well as the establishment of protein quality control protocols in collaboration with the PSI structural biology unit. In addition, there are excellent opportunities to pursue your own research projects in structural biology.
Your profile
You hold a Ph.D. degree in biology or (bio-) chemistry, and have significant experience in high-throughput crystallisation methods and protein crystallography. Practical knowledge in synchrotron related research and in project management is of advantage. If you are self-motivated, flexible, and a good team player this position will offer great opportunities to establish your research career in an exciting and highly multidisciplinary environment.
For further information please contact: Dr Clemens Schulze-Briese, phone +41 56 310 45 33, clemens.schulze@psi.ch or Dr Vincent Olieric, phone +41 56 310 52 33, vincent.olieric@psi.ch
Please submit your application including CV quoting the ref. code by e-mail to elke.baumann@psi.ch or to Paul Scherrer Institut, Human Resources, ref. code 6112-03, Elke Baumann, 5232 Villigen PSI, Switzerland.
[Post Date: July 21, 2010]
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Description:
Fully funded postdoctoral positions at Yale University School of Medicine are available immediately from highly motivated, enthusiastic individuals with a strong interest in the structure, function, and pharmacology of signaling proteins implicated in neurological and neuropsychiatric diseases. We are presently focusing our efforts on central nervous system transporters using a combination of steady-state kinetics, radioligand binding, and X-ray crystallography.
The laboratory is located in newly-renovated space in the Department of Cellular and Molecular Physiology in a highly collaborative environment. We have regular access to a Mosquito crystallization robot, in-house X-ray generator w/ R-axis IV++ detectors, LINUX workstations, and synchrotron beamlines. The lab’s proximity to the renowned W.M. Keck facility will additionally enable the successful candidate to conduct detailed experiments in static and dynamic light scattering, isothermal titration calorimetry, steady-state and stopped-flow fluorometry, and surface plasmon resonance.
Candidates must hold (or soon expect to hold) a Ph.D. in biochemistry, biophysics, or a related field. A strong background in recombinant DNA methods, protein expression and purification, and X-ray crystallography is required. Prior work with membrane proteins, tissue culture, and functional assays is preferred but not necessary. The ideal candidate will also possess excellent oral and written English communication skills and work well in a collaborative environment.
For more information, please contact satinder.k.singh@yale.edu You may also be interested in reading the following review article:
Singh, S.K. (2008) LeuT: a prokaryotic stepping stone on the way to a eukaryotic neurotransmitter transporter structure. Channels 2, 380-389
Applicants should send a CV along with a one-page summary of previous research experience and interests and arrange to have 3 reference letters sent to satinder.k.singh@yale.edu
[Post Date: July 15, 2010]
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Description:
An opening is available in the laboratory of Dr. Stephen Fesik for a postdoc in the field of protein x-ray crystallography. Responsibilities will include protein expression/purification and all aspects of x-ray crystallography, including preparation of protein-inhibitor complexes, crystallization, home/synchrotron data collection, and structure determination. Experience in cloning, site-directed mutagenesis, and the use of crystallization robots is a plus. The ideal candidate should be self-motivated and be able to communicate effectively in a highly collaborative environment.
Please send CV to jason.phan@vanderbilt.edu
[Post Date: July 12, 2010]
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Title:
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Post Doc George Washington University
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Contact:
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Dashuang Shi, PhD
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Phone:
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202-476-5817
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Fax:
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202-476-6014
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Email:
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dshi@cnmcresearch.org
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Description:
A Post-doctoral position in structural biology is available to train in structural biology of proteins of the urea cycle and arginine biosynthesis. The successful candidate will be mentored in generating and testing scientific hypotheses related to structural biology and biochemistry. He/she will work independently on projects under general guidance. Tasks will include design of study, collection and analysis of data, and reporting of results at conferences and in peer-reviewed manuscripts.
Education and Training Required:
Ph.D. or equivalent doctoral degree in molecular biology or related field. Majors Preferred: Biology, Biochemistry, Structural Biology, Molecular Biology, Cell Biology or Microbiology.
Experience Required:
2-3 years of related experience. Experience may have been obtained during doctoral training. Previous supervisory experience not required.
Special Knowledge, Skills, Abilities:
Experience in protein biochemistry and molecular biochemistry and molecular biology methods. Math proficiency and basic statistical skills. Basic UNIX skills. The following specific skills are preferred: construction of plasmids, transfection of cultured cells, gel electrophoresis, PCR analysis, protein purification, RNA and DNA purification, organelle fractionation, SDS/PAGE and Western blotting.
Location: Washington, DC 20010
Please submit CV and 3 references.
Contact:
Dashuang Shi, PhD
Center for Genetic Medicine and Department of Integrative System Biology
Children’s National Medical Center
George Washington University
Washington, DC 20010
[Post Date: July 08, 2010]
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Title:
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Post Doc Protein Crystallography
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Contact:
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Steven Bruner
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Email:
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bruner@ufl.edu
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Description:
A funded postdoctoral position is available at the University of Florida in protein X-ray crystallography. The area of research is the structural biology of natural product antibiotic biosynthesis with a focus on unique enzymology and macromolecule assemblies. The successful candidate will be part of a team using interdisciplinary approaches including synthetic organic chemistry and biochemistry to understand protein function (for example, see Nature, 2007, 447, p. 342-345). The applicant should have a Ph.D. degree in life sciences or related disciplines and a demonstrated record in macromolecular X-ray crystallography. Interested applicants should send by email a cover letter and CV to Prof. Steven Bruner by e-mail at bruner@ufl.edu.
[Post Date: July 06, 2010]
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Description:
Boehringer Ingelheim is currently seeking a talented and innovative Senior Scientist to join our Structural Research department located at our US headquarters in Ridgefield, CT. As a Senior Scientist, you will enable and provide X-ray crystallography support to NCE and NBE projects through the use of structure-based design approaches at all stages of the NCE and NBE discovery process. As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.
Responsibilities:
Enable and provide experimental structural biology input and support that drive NCE and NBE projects to achieve milestone goals.
Maintain all appropriate notebook records of all studies and satisfy all normal lab SOP requirements.
Requirements:
PhD in experimental Structural Biology with two to five years combined post-doctoral and industrial experience, preferably in the pharmaceutical industry or biotechnology sector.
Strong technical skills in protein crystallization. Experience in preparing and characterizing protein samples for crystallization. Demonstrated expertise in the design and implementation of crystallization trials. Demonstrated expertise in the collection and interpretation of X-ray crystallography co-structure data to support NCE optimization.
Experience with the application of structural biology approaches to the design and optimization of NBEs a strong plus.
Experience in the preparation and crystallization of membrane proteins a plus.
Experience with protein-ligand co-structure determination by NMR a plus.
Experience with protein biophysical characterization a plus.
Strong academic performance demonstrating a track record in high-quality, innovative research.
Excellent oral and written communication skills, and good presentation skills.
Ability to work in a fast-paced, goal-oriented, team environment.
Boehringer Ingelheim is firmly committed to ensuring a safe, healthy, productive and efficient work environment for our employees, partners and customers. As part of that commitment, Boehringer Ingelheim conducts pre-employment background investigations and drug screenings. Boehringer Ingelheim is an equal opportunity employer. M/F/D/V
[Post Date: July 01, 2010]
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TECHNICAL SUPPORT
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Tel: 949-425-1321
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Fax: 949-425-1611
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Email: tech@hrmail.com
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LOCATION
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Hampton Research
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34 Journey
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Aliso Viejo, CA 92656-3317
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Toll Free: 800-452-3899
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Tel: 949-425-1321
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Fax: 949-425-1611
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Monday - Friday
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